[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100349206":3},{"organization":4,"outcomesModule":7,"designInfo":29,"detailedDescription":28,"studyPopulation":32,"armGroups":28,"interventions":28,"overallOfficials":28,"centralContacts":33,"locations":39,"responsibleParty":55,"collaborators":28,"id":59,"slug":28,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":28,"enrollmentInfo":67,"targetDuration":28,"studyType":70,"phases":28,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":42,"whyStopped":28,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Modena and Reggio Emilia","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":28},[9],{"measure":10,"description":11,"timeFrame":12},"Esophageal pressure impact on non invasive respiratory support (NRS) failure","Correlation between esophageal pressure values within 24 hours from NRS start and NRS failure","24 hours",[14,17,20,23,25],{"measure":15,"description":16,"timeFrame":12},"Transpulmonary pressure impact on NRS failure","Correlation between transpulmonary pressure values within 24 hours from NRS start and NRS failure",{"measure":18,"description":19,"timeFrame":12},"Dynamic compliance impact on NRS failure","Correlation between dynamic compliance values within 24 hours from NRS start and NRS failure",{"measure":21,"description":22,"timeFrame":12},"Dynamic mechanical power impact on NRS failure","Correlation between dynamic mechanical power within 24 hours from NRS start and NRS failure",{"measure":24,"description":24,"timeFrame":12},"Correlation between nasal pressure (Pnose) and esophageal pressure",{"measure":26,"description":27,"timeFrame":12},"Pnose impact on NRS failure","Correlation between Pnose within 24 hours from NRS start and NRS failure",null,{"allocation":28,"interventionModel":28,"interventionModelDescription":28,"primaryPurpose":28,"observationalModel":30,"timePerspective":31,"maskingInfo":28},"COHORT","PROSPECTIVE","See inclusion criteria",[34],{"name":35,"role":36,"phone":37,"phoneExt":28,"email":38},"Alessandro Marchioni, MD, PhD","CONTACT","00390594225859","marchioni.alessandro@unimore.it",[40],{"facility":41,"status":42,"city":43,"state":28,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"University Hospital of Modena Policlinico","RECRUITING","Modena","41125","Italy","IT",{"type":48,"coordinates":49},"Point",[50,51],10.92539,44.64783,{"lat":51,"lon":50},[54],{"name":35,"role":36,"phone":28,"phoneExt":28,"email":38},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"PRINCIPAL_INVESTIGATOR","Alessandro Marchioni","Principal Investigator","100349206",false,"NCT03826797","Correlation Between Trans Esophageal Pressure and Non-invasive Respiratory Support Failure in Patients With Acute Hypoxic Respiratory Failure","TEMPO","Inclusion Criteria:\n\n* Age \\>18 years\n* Acute hypoxic respiratory failure (P\u002FF \\\u003C 200)\n\nExclusion Criteria:\n\n* Acute pulmonary edema\n* Chest wall deformities\n* Immediate need for Mechanical Ventilation\n* Pregnancy\n* Hypercapnic RF","ALL","18 Years",{"count":68,"type":69},300,"ESTIMATED","OBSERVATIONAL","This study aims at assessing the correlation between trans esophageal pressure and related respiratory mechanics (including, among others, nasal pressure-Pnose) and non-invasive respiratory support failure in patients with acute hypoxic respiratory failure of different etiology (including COVID-19).",[73],"Acute Respiratory Failure",[75,76,77],"Non invasive ventilation","Esophageal pressure","Transpulmonary pressure","2023-03-22",{"date":80,"type":81},"2023-03-23","ACTUAL",{"date":83,"type":81},"2016-10-16",{"date":85,"type":69},"2027-12-31",{"name":5,"class":6},1]