Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment
ConditionParkinson Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40+
SponsorVanderbilt University Medical Center
About this trial
The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
Eligibility criteria
Qualifiers
Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
Planned clinical electrode trajectory that contacts caudate
Age greater than or equal to 40
Diagnosis of Parkinson's disease
Disqualifiers
Age less than 40
Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
Movement disorder other than Parkinson's disease
Trial design
Treatments tested in this trial
- Neurophysiology recordings
- Neural stimulation
Treatment groups
75 Participants
are divided into 1 treatment groupLocations
1Vanderbilt University Medical Center37212, NashvilleTennessee, United States
Sponsors and collaborators
Vanderbilt University Medical Center
Lead sponsor
Source ClinicalTrials.gov