The purpose of this study is to evaluate functional and aesthetic outcomes of combined facial and upper extremity composite tissue allografts on patients who have not achieved functional and aesthetic outcomes with conventional reconstructive surgical strategies and prosthetic devices.
Signed and dated all required Institutional Review Board (IRB) approved consent forms.
Male or female recipient between the ages of 18-64 years. Recipients do not need to be of the same sex as the donor.
Facial composite tissue defect requiring facial transplantation as determined by the treating Plastic and Reconstructive Surgeon. Inclusive facial functional subunit tissue loss. Including but not limited to irreparable peri-oral, peri-orbital, and peri-nasal damage.
Missing part of one or both hands and forearms.
Uncontrolled infection or severe concomitant diseases which would exclude the recipient from transplantation
Serious co-morbidities
Positive serology for HIV; Hepatitis B Antigen
Active malignancy within 5 years with the exclusion of non-melanoma
NYU Langone Health
Lead sponsor