[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100543295":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":27,"centralContacts":32,"locations":38,"responsibleParty":68,"collaborators":10,"id":70,"slug":10,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Sensorion","INDUSTRY",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients with adulthood-onset bilateral sensorineural hearing loss (SNHL)",null,[12],"Genetic: Genotyping",{"label":14,"type":10,"description":10,"interventionNames":15},"Patients that carry mutations in the gene GJB2 from patients with adulthood-onset bilateral SNHL",[16],"Other: Audiological assessments",[18,23],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"GENETIC","Genotyping","Genotyping to determine if patients present mutations to the gene GJB2.",[9],{"type":24,"name":25,"description":25,"armGroupLabels":26,"otherNames":10},"OTHER","Audiological assessments",[14],[28],{"name":29,"affiliation":30,"role":31},"Maya ELZIERE, MD","Hôpital Eureopéen Marseille","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Lionel HOVSEPIAN, MD","CONTACT","+33786311376","lionel.hovsepian@sensorion-pharma.com",[39,55],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"The University of South Florida Board of Trustees","RECRUITING","Tampa","Florida","33620","United States",{"type":47,"coordinates":48},"Point",[49,50],-82.45843,27.94752,{"lat":50,"lon":49},[53],{"name":54,"role":35,"phone":10,"phoneExt":10,"email":10},"Victoria Sanchez, MD",{"facility":56,"status":41,"city":57,"state":10,"zip":58,"country":59,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"CHU Gui de Chauliac","Montpellier","34295","France",{"type":47,"coordinates":61},[62,63],3.87635,43.61093,{"lat":63,"lon":62},[66],{"name":67,"role":35,"phone":10,"phoneExt":10,"email":10},"Frederic Venail, Pr",{"type":69,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100543295",false,"NCT06354010","Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis","SONG","Inclusion Criteria:\n\n1. Female or Male patients ≥30 and ≤55 years old\n2. Bilateral hearing loss first noticed after the age of 16 years old\n3. Documented genotyping results showing mutations in GJB2 gene.\n\nExclusion Criteria:\n\n1. Deafness with a known, non-genetic cause\n2. To the opinion of the investigator, unable and\u002For unwilling to comply with all the protocol requirements and\u002For study procedures","ALL","30 Years","55 Years",{"count":80,"type":81},100,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.",[85],"Sensorineural Hearing Loss, Bilateral",[87,88,89,90,91,92,74,93,94],"Adulthood-onset bilateral sensorineural hearing loss","GJB2","Presbycusis","hearing impairement","Deafness","Connexin 26","Genetic deafness","Adult deafness","2026-05-04",{"date":97,"type":98},"2026-05-08","ACTUAL",{"date":100,"type":98},"2024-06-14",{"date":102,"type":81},"2027-07",{"name":5,"class":6},2]