[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100271373":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":110,"collaborators":21,"id":112,"slug":21,"hasResults":113,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":113,"sex":119,"minAge":120,"maxAge":121,"enrollmentInfo":122,"targetDuration":21,"studyType":125,"phases":126,"briefSummary":128,"conditions":129,"keywords":131,"overallStatus":44,"whyStopped":21,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":143},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de la Réunion","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Open-label","EXPERIMENTAL","Device: ultrasonography and diuretic renography Bilateral ultrasonography to measure the antero-posterior renal pelvic diameter (APRPD) in both positions.\n\nDiuretic renography to measure the cortical transit time",[13,14],"Device: ultrasonography","Device: diuretic renography",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DEVICE","ultrasonography","bilateral ultrasonography to measure the antero-posterior renal pelvic diameter (APRPD) in both positions.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"diuretic renography","diuretic renography to measure the cortical transit time.",[9],[27],{"name":28,"affiliation":29,"role":30},"Luke Harper, MD","University Hospital, Bordeaux","PRINCIPAL_INVESTIGATOR",[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Lucie Auzanneau","CONTACT","0262359949","+262","lucie.auzanneau@chu-reunion.fr",{"name":39,"role":34,"phone":21,"phoneExt":21,"email":40},"Valérie Fontaine","promotion.drci@chu-reunion.fr",[42,57,70,84,97],{"facility":43,"status":44,"city":45,"state":21,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"CHU de Bordeaux","RECRUITING","Bordeaux","33076","France",{"type":49,"coordinates":50},"Point",[51,52],-0.58046,44.84124,{"lat":52,"lon":51},[55],{"name":56,"role":34,"phone":21,"phoneExt":21,"email":37},"Lucie AUZANNEAU",{"facility":58,"status":44,"city":59,"state":21,"zip":60,"country":47,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"CHU de Limoges","Limoges","87000",{"type":49,"coordinates":62},[63,64],1.24759,45.83362,{"lat":64,"lon":63},[67,68],{"name":56,"role":34,"phone":21,"phoneExt":21,"email":21},{"name":69,"role":30,"phone":21,"phoneExt":21,"email":21},"Laurent FOURCADE, MD",{"facility":71,"status":72,"city":73,"state":21,"zip":74,"country":47,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"CHU de Nantes","NOT_YET_RECRUITING","Nantes","44000",{"type":49,"coordinates":76},[77,78],-1.55336,47.21725,{"lat":78,"lon":77},[81,82],{"name":56,"role":34,"phone":21,"phoneExt":21,"email":37},{"name":83,"role":30,"phone":21,"phoneExt":21,"email":21},"Marc-David LECLAIR, MD",{"facility":85,"status":72,"city":86,"state":21,"zip":87,"country":47,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"CHU de Rennes","Rennes","35023",{"type":49,"coordinates":89},[90,91],-1.67431,48.11109,{"lat":91,"lon":90},[94,95],{"name":56,"role":34,"phone":21,"phoneExt":21,"email":21},{"name":96,"role":30,"phone":21,"phoneExt":21,"email":21},"Alexis ARNAUD, MD",{"facility":98,"status":44,"city":99,"state":21,"zip":100,"country":47,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Centre Hospitalier Universitaire de La Réunion","Saint-Denis","97400",{"type":49,"coordinates":102},[103,104],2.35387,48.93564,{"lat":104,"lon":103},[107,108],{"name":33,"role":34,"phone":21,"phoneExt":36,"email":37},{"name":109,"role":30,"phone":21,"phoneExt":21,"email":21},"Frédérique SAUVAT, MD, PhD",{"type":111,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100271373",false,"NCT02812212","CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome","Cortical Transit Time on Diuretic Renogram as an Early Marker of Significant Obstruction in Antenatally Detected Uretero-pelvic Junction Syndrome","JUMP","Inclusion Criteria:\n\nInfants:\n\n* Aged of 4 to 8 weeks of life\n* Presenting an ureteropelvic junction obstruction (UPJO) detected before birth by ultrasound\n* Presenting an UPJO, defined by an Antero-Posterior Renal Pelvic Diameter greater or equal to 15 mm, confirmed by ultrasound post-natally between the 1st and 15th day of life\n* Presenting a unilateral UPJO\n* whose legal representatives have provided a signed free and informed written consent for their infant's participation\n* whose at least one of his legal representative is affiliated to national social security\n\nExclusion Criteria:\n\nInfants presenting:\n\n* A bilateral UPJO\n* An ureteral dilatation\n* An associated contralateral uropathy\n* A solitary kidney\n* A renal insufficiency\n* Severe associated disabilities ( ie polymalformation syndromes)\n* A concomitant participation in another trial\n* A contraindication to furosemide (acute renal insufficiency, hepatic encephalopathy, hypovolemia or dehydration, severe hypokalemia, severe hyponatremia)\n* A contraindication to the radionuclide marker (hypersensitivity to the active substance or to excipients)","ALL","4 Weeks","8 Weeks",{"count":123,"type":124},75,"ESTIMATED","INTERVENTIONAL",[127],"NA","Cortical transit time on diuretic renogram as an early marker of significant obstruction in antenatally detected uretero-pelvic junction syndrome",[130],"Ureteropelvic Junction Obstruction",[132,133],"ureteropelvic junction obstruction","cortical transit time","2022-09-27",{"date":136,"type":137},"2022-09-29","ACTUAL",{"date":139,"type":137},"2017-11-28",{"date":141,"type":124},"2027-04",{"name":5,"class":6},5]