Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age10-17
SponsorSt. Jude Children's Research Hospital

About this trial

The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain education in reducing chronic pain and improving daily functioning in adolescent survivors of pediatric cancer.

This randomized study led by St. Jude Children's Research Hospital will involve 228 participants (114 adolescent survivors and 114 caregivers) across four U.S. hospitals. Outcomes include pain reduction, improved function, and the role of social determinants of health. Assessments occur at baseline, post-treatment, and 3-month follow-up.

Eligibility criteria

Qualifiers

Adolescent Participants

10-17-year-old survivors of childhood cancer or those who received cancer directed therapies (e.g., Langerhan's Histiocytosis)

At least one-year post treatment completion

Pain present for 3 months or longer

Disqualifiers

Adolescent Participants

Serious comorbid psychiatric condition

Current substance abuse as determined by the Substance Use Screening Questionnaire

History of development delay or significant cognitive impairment

Trial design

Treatments tested in this trial

  • Cognitive Behavioral Therapy (CBT)
  • Education
  • Questionnaires

Treatment groups

228 Participants
are divided into 2 treatment groups

Locations

1
St. Jude Children's Research Hospital38105, MemphisTennessee, United States

Sponsors and collaborators

St. Jude Children's Research Hospital

Lead sponsor