Cytapheresis of Volunteer Donors
ConditionHealthy Volunteers
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-120
SponsorNational Institute on Aging (NIA)
About this trial
Background:
\- National Institute on Aging researchers are looking at studies that require large numbers of white blood cells for lab use. Standard blood samples do not provide enough white blood cells for these studies. Researchers want to use cytapheresis to collect white blood cells from volunteer donors. This procedure can collect larger amounts of white blood cells and reduce the amount of fluid and other cells that are lost.
Objectives:
\- To use cytapheresis to collect white blood cells for study.
Eligibility:
\- Healthy blood donors at least 18 years of age.
Design:
* Participants will be screened according to the usual blood donation procedures. * Participants will provide white blood cells through cytapheresis. The blood cells will be collected in a machine that separates the white blood cells from the rest of the blood. The rest of the blood will be returned to the donor. * Participants may have this type of donation every 56 days (six times per year). They will be asked to become a repeat donor. A donation schedule may be set up. * Once a year, participants will have blood tests to continue to be eligible as a donor.
Eligibility criteria
Qualifiers
Normal healthy males and females, age 18 years and older
Adequate venous access in bilateral upper extremities to accommodate at least a #18 gauge dialysis needle.
Willingness and ability to come to the NIA Apheresis Unit at Harbor Hospital in Baltimore for a blood collection procedure approximately every 56 days.
Disqualifiers
Unable to verify identification of volunteer by state issued ID card, driver s license, or military ID. Participants earning greater than $600.00/year are issued a 1099 form, therefore, positive identification is required.
Unable to provide informed consent
Weight less than 110 pounds as mandated by AABB guidelines.
Chronic Immunosuppressive medications such as Steroids, Cellcept or Sirolimus. Steroids given for minor illness ok if taken more than 6 weeks before any cytapheresis procedure. Immunosuppressive medications may not be used at the time of the cytapheresis procedure as they decrease circulating white blood cells.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
10,000 Participants
are grouped into 1 trial groupLocations
1National Institute of Aging, Clinical Research Unit21224, BaltimoreMaryland, United States
Sponsors and collaborators
National Institute on Aging (NIA)
Lead sponsor
Source ClinicalTrials.gov