About this trial

The results of the current studies to determine the optimal strategy for metastatic gastric cancer remain contrversial worldwide.

Hypothesis: Cytoreductive Gastrectomy After Systemic Therapy will improve survival time for metastasis gastric cancer compared to Systemic Therapy alone.

Eligibility criteria

Qualifiers

Age 18-75

GCLM detected on surgical exploration and demonstrated by histology or cytology

Localized peritoneal carcinomatosis (P1 or P2 score), according to the classification of the Japanese Research Society for Gastric Cancer

Liver metastasis lesions of maximum diameter ≤5 cm

Disqualifiers

Any extra-abdominal metastasis at diagnosis or during systemic treatment.

Past history of malignancy other than gastric cancer diagnosed in the last 5 years except for basal cell carcinoma of skin or preinvasive cancer of cervix

Patients in the reproductive age who declined to use an adequate means of contraception

Significant disease or conditions which, in the investigator's opinion, would exclude patient from the study

Trial design

Treatments tested in this trial

  • Cytoreductive Gastrectomy

Treatment groups

250 Participants
are divided into 2 treatment groups

Locations

1
University Medical Center700000, Ho Chi Minh CityHo Chi Minh, Vietnam

Sponsors and collaborators

University Medical Center Ho Chi Minh City (UMC)

Lead sponsor