About this trial

This study aims to explore the role of dagliflozin in preserving the residual renal function(RRF) in peritoneal dialysis (PD) patients.

Eligibility criteria

Qualifiers

Patients with PD duration between 1 month and 3 months.

Patients aged between 18 and 75 years.

Voluntary signing of informed consent.

Stable use of a maximum tolerated dose of RAAS inhibitors for one month if hypertension is present.

Disqualifiers

Pregnant and lactating women.

Patients with type 1 diabetes mellitus.

Patients with type 2 diabetes mellitus who have experienced diabetic ketoacidosis in the past.

Patients with chronic liver disease, including non-alcoholic fatty liver disease, cirrhosis, ALT > 120 IU/L, and other clinically confirmed severe liver diseases.

Trial design

Treatments tested in this trial

  • Dapagliflozin

Treatment groups

70 Participants
are divided into 2 treatment groups

Locations

1
Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospita610000, ChengduSichuan, China

Sponsors and collaborators

Sichuan Academy of Medical Sciences

Lead sponsor