[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523194":3},{"organization":4,"outcomesModule":7,"designInfo":17,"detailedDescription":16,"studyPopulation":20,"armGroups":21,"interventions":27,"overallOfficials":16,"centralContacts":32,"locations":38,"responsibleParty":55,"collaborators":16,"id":59,"slug":16,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":16,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":16,"maxAge":16,"enrollmentInfo":66,"targetDuration":16,"studyType":69,"phases":16,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":41,"whyStopped":16,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"First Affiliated Hospital of Chongqing Medical University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":16},[9,13],{"measure":10,"description":11,"timeFrame":12},"Overall survival（OS）","the time from the date of surgery to death from any cause or the date of last contact (censored observation) at the date of data cut-off.","up to 10 years",{"measure":14,"description":15,"timeFrame":12},"Recurrence free survival（RFS)","the time from the date of surgery to the date of first documented disease recurrence. Patients without recurrence at the time of analysis will be censored.",null,{"allocation":16,"interventionModel":16,"interventionModelDescription":16,"primaryPurpose":16,"observationalModel":18,"timePerspective":19,"maskingInfo":16},"COHORT","RETROSPECTIVE","patients with pathologically confirmed MIBC who underwent radical cystectomy",[22],{"label":23,"type":16,"description":24,"interventionNames":25},"MIBC","patients with pathologically confirmed MIBC after radical cystectomy",[26],"Other: develop and validate a deep learning radiomics model based on preoperative enhanced CT image",[28],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":16},"develop and validate a deep learning radiomics model based on preoperative enhanced CT image","develop and validate a deep learning radiomics model based on preoperative enhanced CT to predict postoperative survival in MIBC",[23],[33],{"name":34,"role":35,"phone":36,"phoneExt":16,"email":37},"Zongjie Wei","CONTACT","023-89012557","wzj9846@163.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Department of Urology, The First Affiliated Hospital of Chongqing Medical University","RECRUITING","Chongqing","Chongqing Municipality","400016","China","CN",{"type":48,"coordinates":49},"Point",[50,51],106.55771,29.56026,{"lat":51,"lon":50},[54],{"name":34,"role":35,"phone":36,"phoneExt":16,"email":37},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":16,"oldOrganization":16},"PRINCIPAL_INVESTIGATOR","Mingzhao Xiao","Professor","100523194",false,"NCT06092450","Deep Learning Radiomics Model for Predicting Post-cystectomy Outcome in Muscle Invasive Bladder Cancer","Deep Learning Radiomics Model for Predicting Post-cystectomy Outcome From Preoperative CT in Muscle Invasive Bladder Cancer","Inclusion Criteria:\n\n* patients with pathologically confirmed MIBC after radical cystectomy;\n* contrast-CT scan less than two weeks before surgery;\n* complete CT image data and clinical data.\n\nExclusion Criteria:\n\n* patients who received neoadjuvant therapy;\n* non-urothelial carcinoma;\n* poor quality of CT images;\n* incomplete clinical and follow-up data.","ALL",{"count":67,"type":68},500,"ESTIMATED","OBSERVATIONAL","Muscle invasive bladder cancer (MIBC) has a poor prognosis even after radical cystectomy. Postoperative survival stratification based on radiomics and deep learning may be useful for treatment decisions to improve prognosis. This study was aimed to develop and validate a deep learning radiomics model based on preoperative enhanced CT to predict postoperative survival in MIBC.",[72],"Bladder Cancer",[74,75,76,77],"Tomography, X-ray computed","Muscle-invasive bladder cancer","Radiomics","Deep Learning","2025-05-27",{"date":80,"type":81},"2025-05-31","ACTUAL",{"date":83,"type":81},"2023-08-01",{"date":85,"type":68},"2025-06-01",{"name":5,"class":6},1]