[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100504386":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":46,"collaborators":10,"id":49,"slug":10,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":50,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute Respiratory Distress Syndrome",null,"Adults admitted to ICU with ARDS confirmed according to Berlin Definition",[13],"Device: Masimo O3 NIRS cerebral oximetry and SedLine processed EEG",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Masimo O3 NIRS cerebral oximetry and SedLine processed EEG","Non-invasive neuromonitoring device for observational study",[9],[21],{"name":22,"affiliation":5,"role":23},"Asher Mendelson, MD PhD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","204-787-8059","asher.mendelson@umanitoba.ca",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Health Sciences Centre Winnipeg","RECRUITING","Winnipeg","Manitoba","R3T2N2","Canada",{"type":38,"coordinates":39},"Point",[40,41],-97.14704,49.8844,{"lat":41,"lon":40},[44],{"name":22,"role":26,"phone":45,"phoneExt":10,"email":28},"2047878059",{"type":23,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Asher Mendelson","Assistant Professor","100504386",false,"NCT05847634","Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis","Inclusion Criteria:\n\n* Adult patient admitted to the ICU\n* ARDS confirmed according to the Berlin Definition\n* Invasive mechanical ventilation\n* Deep sedation and\u002For neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team\n* Application of monitoring devices feasible\n\nExclusion Criteria:\n\n* More than 24 hours elapsed since ICU admission\n* Death is deemed imminent and inevitable during the next 24 hours\n* Known allergy to a textile component of the device\n* Consent declined from patient or authorized third party\n* The treating clinician believes that participation in the study would not be in the best interest of the patient","ALL","18 Years",{"count":57,"type":58},40,"ESTIMATED","OBSERVATIONAL","Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.",[62],"ARDS, Human",[64,65,66,67,9],"Near-Infrared Spectroscopy","Depth of Sedation","Intensive Care Unit","Electroencephalography","2024-12-03",{"date":70,"type":71},"2024-12-06","ACTUAL",{"date":73,"type":71},"2024-11-25",{"date":75,"type":58},"2026-01",{"name":5,"class":6},1]