[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100338853":3},{"organization":4,"outcomesModule":7,"designInfo":33,"detailedDescription":36,"studyPopulation":37,"armGroups":38,"interventions":32,"overallOfficials":42,"centralContacts":46,"locations":55,"responsibleParty":157,"collaborators":159,"id":169,"slug":32,"hasResults":170,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":174,"eligibilityCriteria":175,"healthyVolunteers":170,"sex":176,"minAge":32,"maxAge":32,"enrollmentInfo":177,"targetDuration":180,"studyType":181,"phases":32,"briefSummary":182,"conditions":183,"keywords":185,"overallStatus":58,"whyStopped":32,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":191,"completionDateStruct":193,"leadSponsor":195,"locationsCount":196},{"fullName":5,"class":6},"Fundació Institut Germans Trias i Pujol","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":32},[9,13],{"measure":10,"description":11,"timeFrame":12},"Clinical changes","Changes in clinical status","timepoints 0 (at inclusion), at month 2 and month 6 (and month 12 if MDR\u002FXDR)",{"measure":14,"description":15,"timeFrame":12},"Microbiological changes","Changes in microbiological cultures",[17,20,23,26,29],{"measure":18,"description":19,"timeFrame":12},"Changes in Biomarkers values","Changes in the biomarkers along time assessed by using analyzing parameters in blood and urine samples (by ELISA and LUMINEX)",{"measure":21,"description":22,"timeFrame":12},"Radiological Score Value","Changes in the BCN-SA Radiological Score Value. This Score assesses the sum of acute and chronic findings in the chest X-ray. Per each finding, a maximum score of 8 is recorded. The total score value is calculated by adding all the individual findings score values. Higher values of total score represent a worse outcome.",{"measure":24,"description":25,"timeFrame":12},"Changes in SGRQ score","Changes in Health Quality of Life measures along time assessed by using the Saint George's Respiratory Questionnaire (SGRQ, numeric score). It measures 3 subscales (symptoms\u002Factivity\u002Fimpacts) and The Total score is calculated by summing all positive responses in the questionnaire and expressing the result as a percentage of the total weight for the questionnaire. Higher values represent a worse outcome.",{"measure":27,"description":28,"timeFrame":12},"Changes in Kessler-10 score","Changes in Health Quality of Life measures along time assessed by using the questionnaire Kessler-10 (K10, numeric score). Higher values represent a worse outcome.",{"measure":30,"description":31,"timeFrame":12},"Changes in Health Quality of Life measures along time using BCN-Q questionnaire","Changes in Health Quality of Life measures along time using BCN-Q questionnaire (descriptive questionnaire).",null,{"allocation":32,"interventionModel":32,"interventionModelDescription":32,"primaryPurpose":32,"observationalModel":34,"timePerspective":35,"maskingInfo":32},"COHORT","PROSPECTIVE","Tuberculosis is a chronic infectious disease that affects 10 million people, there are 300 new cases 300 in the city of Barcelona, every year. Tuberculosis has serious consequences at public health level. It is associated with other diseases, and generated and influenced by many social and psychological factors. This study aims to stage tuberculosis disease by a novel integrative approach.","TB patients which clinical management is done at the following clinical centers: Servicios Clínicos, Hospital Universitari Vall d'Hebron-Drassanes or Hospital Universitari Germans Trias i Pujol.",[39],{"label":40,"type":32,"description":41,"interventionNames":32},"TB patients","TB patients diagnosed and followed-up in Barcelona, at the following Hospitals\u002FClinics: Servicios Clínicos, Hospital Universitari Germans Trias i Pujol, Hospital Universitari Vall d'Hebron-Drassanes, Hospital del Mar.",[43],{"name":44,"affiliation":5,"role":45},"Cris Vilaplana, MD, PhD","PRINCIPAL_INVESTIGATOR",[47,51],{"name":44,"role":48,"phone":49,"phoneExt":32,"email":50},"CONTACT","934978677","cvilaplana@gmail.com",{"name":52,"role":48,"phone":53,"phoneExt":32,"email":54},"Laura Villegas","+34934978681","secretary.ute@gmail.com",[56,77,90,108,133],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Hospital Universitari Germans Trias i Pujol","RECRUITING","Badalona","Barcelona","08916","Spain","ES",{"type":65,"coordinates":66},"Point",[67,68],2.24741,41.45004,{"lat":68,"lon":67},[71,73,76],{"name":72,"role":48,"phone":32,"phoneExt":32,"email":32},"Zoran Stojanovic, MD, PhD",{"name":74,"role":75,"phone":32,"phoneExt":32,"email":32},"Cristina Prat, MD, PhD","SUB_INVESTIGATOR",{"name":72,"role":45,"phone":32,"phoneExt":32,"email":32},{"facility":78,"status":58,"city":79,"state":60,"zip":80,"country":62,"countryCode":63,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Hospital Sant Joan de Déu","Esplugues de Llobregat","08950",{"type":65,"coordinates":82},[83,84],2.08809,41.37732,{"lat":84,"lon":83},[87,89],{"name":88,"role":48,"phone":32,"phoneExt":32,"email":32},"Antoni Noguera, MD, PhD",{"name":88,"role":45,"phone":32,"phoneExt":32,"email":32},{"facility":91,"status":58,"city":60,"state":32,"zip":92,"country":62,"countryCode":63,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Hospital del Mar","08003",{"type":65,"coordinates":94},[95,96],2.15899,41.38879,{"lat":96,"lon":95},[99,101,102,104,106],{"name":100,"role":48,"phone":32,"phoneExt":32,"email":32},"Neus Jové, MD",{"name":100,"role":45,"phone":32,"phoneExt":32,"email":32},{"name":103,"role":75,"phone":32,"phoneExt":32,"email":32},"Francisca Sánchez, MD",{"name":105,"role":75,"phone":32,"phoneExt":32,"email":32},"Marisol Domínguez, MD",{"name":107,"role":75,"phone":32,"phoneExt":32,"email":32},"Núria López, MD",{"facility":109,"status":58,"city":60,"state":32,"zip":32,"country":62,"countryCode":63,"cosmosGeoPoint":110,"geoPoint":112,"contacts":113},"Hospital Universitari Vall d'Hebron-Drassanes",{"type":65,"coordinates":111},[95,96],{"lat":96,"lon":95},[114,116,117,119,121,123,125,127,129,131],{"name":115,"role":48,"phone":32,"phoneExt":32,"email":32},"Adrián Sánchez, MD, PhD",{"name":115,"role":45,"phone":32,"phoneExt":32,"email":32},{"name":118,"role":75,"phone":32,"phoneExt":32,"email":32},"Malú De Souza, MD, PhD",{"name":120,"role":75,"phone":32,"phoneExt":32,"email":32},"Jiménez, MD",{"name":122,"role":45,"phone":32,"phoneExt":32,"email":32},"Pere Soler, MD, PhD",{"name":124,"role":75,"phone":32,"phoneExt":32,"email":32},"Andrea Martín, MD",{"name":126,"role":75,"phone":32,"phoneExt":32,"email":32},"Antoni Soriano, MD, PhD",{"name":128,"role":75,"phone":32,"phoneExt":32,"email":32},"Teresa Tórtola, MD, PhD",{"name":130,"role":75,"phone":32,"phoneExt":32,"email":32},"Israel Molina, MD, PhD",{"name":132,"role":75,"phone":32,"phoneExt":32,"email":32},"Núria Saborit",{"facility":134,"status":58,"city":60,"state":32,"zip":32,"country":62,"countryCode":63,"cosmosGeoPoint":135,"geoPoint":137,"contacts":138},"Servicios Clínicos de Barcelona",{"type":65,"coordinates":136},[95,96],{"lat":96,"lon":95},[139,141,143,145,147,149,151,153,155],{"name":140,"role":48,"phone":32,"phoneExt":32,"email":32},"Joan Pau Millet",{"name":142,"role":45,"phone":32,"phoneExt":32,"email":32},"Joan Pau Millet, MD, PhD",{"name":144,"role":75,"phone":32,"phoneExt":32,"email":32},"Xavier Casas, MD",{"name":146,"role":75,"phone":32,"phoneExt":32,"email":32},"Israel Molina, MD",{"name":148,"role":75,"phone":32,"phoneExt":32,"email":32},"Gónzalez-Díaz, MD",{"name":150,"role":75,"phone":32,"phoneExt":32,"email":32},"Maldonado, MD",{"name":152,"role":75,"phone":32,"phoneExt":32,"email":32},"Altet, MD",{"name":154,"role":75,"phone":32,"phoneExt":32,"email":32},"Jaume Ollé-Goig, MD",{"name":156,"role":75,"phone":32,"phoneExt":32,"email":32},"Núria Forcades, MD",{"type":158,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[160,163,164,166,168],{"name":161,"class":162},"Hospital Universitari Vall d'Hebron (Drassanes)","UNKNOWN",{"name":134,"class":162},{"name":165,"class":6},"Germans Trias i Pujol Hospital",{"name":167,"class":6},"Hospital Sant Joan de Deu",{"name":91,"class":6},"100338853",false,"NCT03691883","Design of an Integrative Algorithm for Staging Tuberculosis","Design of an Integrative Algorithm for Staging Tuberculosis to Improve Clinical Management.","STAGE-TB","Inclusion Criteria:\n\n* TB diagnosis (all forms), microbiologically confirmed (by AFB+, GenXpert+ or Culture+)\n* Clinical management of the patients being done at Servicios Clínicos, Hospital Universitari Vall d'Hebron-Drassanes or Hospital Universitari Germans Trias i Pujol.\n\nExclusion Criteria:\n\n* Not consenting to data\u002Fsamples 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With serious consequences at public health level, it is associated with other diseases, and generated and influenced by many social and psychological factors. This study aims to stage tuberculosis disease by an integrative approach.",[184],"Tuberculosis",[186],"tuberculosis, infectious diseases","2024-12-22",{"date":189,"type":190},"2024-12-27","ACTUAL",{"date":192,"type":190},"2018-04-19",{"date":194,"type":179},"2026-12-31",{"name":5,"class":6},5]