[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499804":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":34,"responsibleParty":48,"collaborators":51,"id":55,"slug":20,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":20,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":20,"enrollmentInfo":63,"targetDuration":20,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":74,"overallStatus":37,"whyStopped":20,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pharmacist-led opioid taper intervention","EXPERIMENTAL","The participant will attempt to taper their opioid dose by \\~50% during the 4-6 week preoperative period. Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.",[13],"Behavioral: opioid taper",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","opioid taper","The participant will attempt to taper their opioid dose by \\~50% during the 4-6 week preoperative period",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Kevin R Riggs, MD","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","205-934-0778","kriggs@uabmc.edu",{"name":31,"role":27,"phone":32,"phoneExt":20,"email":33},"Shakristal Williams","205-934-2304","shakristalwilliams@uabmc.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":20},"UAB Hospital-Highlands","RECRUITING","Birmingham","Alabama","35205","United States",{"type":43,"coordinates":44},"Point",[45,46],-86.80249,33.52066,{"lat":46,"lon":45},{"type":24,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Kevin Riggs","Assistant Professor",[52],{"name":53,"class":54},"National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)","NIH","100499804",false,"NCT05788016","Developing an Opioid Taper Intervention Before Total Joint Arthroplasty","Developing and Testing an Opioid Taper Intervention Before Total Knee Arthroplasty: Phase 2 Intervention Development","Inclusion Criteria:\n\n* decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks\n* currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months\n* have a reliable telephone number for contact\n* speaks English\n\nExclusion Criteria:\n\n* Taking opioid medications that include:\n\n  * Buprenorphine\n  * Methadone\n  * Long-acting formulations of opioid pain medications (e.g., extended-release oxycodone and extended-release morphine)\n  * Transdermal formations of opioid pain medications (e.g., fentanyl patches)","ALL","18 Years",{"count":64,"type":65},45,"ESTIMATED","INTERVENTIONAL",[68],"NA","The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are:\n\n* Is the intervention feasible and acceptable to patients?\n* Does the intervention result in a decrease in opioid dose during the preoperative period?\n\nParticipants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.",[71,72,73],"Arthritis Knee","Arthritis Hip","Chronic Pain",[75],"Opioids","2026-05-27",{"date":78,"type":79},"2026-05-29","ACTUAL",{"date":81,"type":79},"2024-01-10",{"date":83,"type":65},"2027-07-01",{"name":5,"class":6},1]