Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorZhejiang University

About this trial

Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients. Aspiration of gastric contents represents a critical anesthesia-related complication during the perioperative period, carrying substantial implications for anesthetic management. With the growing volume of sedated gastroscopy procedures, predicting gastric retention has become an urgent clinical priority. This prospective study aims to establish a standardized gastric residual volume (GRV) grading system to evaluate both the volume of retained gastric contents and its contributing factors in patients undergoing upper gastrointestinal endoscopy. We will systematically assess the impact of demographic characteristics, comorbidities, and medication history on gastric emptying function. This study will facilitate establishment of an endoscopy-based simplified assessment system for gastric retention.

Eligibility criteria

Qualifiers

Age ≥18 years.

Patients scheduled for elective sedated gastroscopy or sedated gastro-colonoscopy.

Participant provides informed consent.

Disqualifiers

Acute upper gastrointestinal bleeding (active hematemesis, melena, or confirmed UGIB within 24h).

Emergency endoscopic procedures

Known pregnancy or lactation

Subjects deemed ineligible by investigators

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

5,000 Participants
are grouped into 1 trial group

Locations

3
The First Affiliated Hospital, Zhejiang University School of Medicine310000, HangzhouZhejiang, China
The Second Affiliated Hospital of Jiaxing University314000, JiaxingZhejiang, China
The Fifth Affiliated Hospital of Wenzhou Medical University323000, LishuiZhejiang, China

Sponsors and collaborators

Zhejiang University

Lead sponsor