[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100303662":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":20,"studyPopulation":21,"armGroups":22,"interventions":17,"overallOfficials":17,"centralContacts":29,"locations":39,"responsibleParty":61,"collaborators":63,"id":76,"slug":17,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":17,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":17,"studyType":88,"phases":17,"briefSummary":89,"conditions":90,"keywords":17,"overallStatus":42,"whyStopped":17,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Beijing Institute of Heart, Lung and Blood Vessel Diseases","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":17},[9,13],{"measure":10,"description":11,"timeFrame":12},"Dignosis of each participant","1. Patients with Aneurysm\u002FDissection had image information from ultrasound cardiograms and computed tomography to confirm the final diagnosis.\n2. AMI if they had chest pain lasting \\>20 min, diagnostic serial ECG changes comprising new pathological Q waves or ST-segment and T-wave changes, and a plasma creatine kinase-MB elevation greater than twice the normal level or cardiac troponin I (cTnI) level greater than 0.1 ng\u002FmL.\n3. Diagnosis of PE was confirmed by positive spiral computed tomography or pulmonary angiography, a high probability on ventilation perfusion scintigraphy, or a proximal deep vein thrombosis documented on compression ultrasonography or angiography.","These data is collected from the cases' medical record in an average of 6 month after the sample recruiting",{"measure":14,"description":15,"timeFrame":16},"Prognosis of each participant","Prognosis information including all-cause mortality and in-hospital mortality.","These data is collected from the cases' medical record or during follow-up visit at 2-4 years after discharge.",null,{"allocation":17,"interventionModel":17,"interventionModelDescription":17,"primaryPurpose":17,"observationalModel":19,"timePerspective":6,"maskingInfo":17},"COHORT","The study aims to investigate the role of candidate biomarkers in the diagnosis and prognosis of AA and AD. In the diagnosis part, we begin with a discovery phase where individually matched case-control study. Patients within each disease outcomes (i.e. AD, AMI, PE, AA without AD and healthy controls) are age and sex matched and retrospectively included.In the prognosis part of the study, patients with confirmed AA and AD are enrolled. The primary outcome is the all-cause mortality based on the death certificates. The secondary outcome is the in-hospital mortality according to the patients'medical records.","These cohorts consist of patients who was diagnosed as thoracic aortic aneurysm\u002Fdissection or initial suspicion of having thoracic aortic aneurysm\u002Fdissection.",[23,25,27],{"label":24,"type":17,"description":17,"interventionNames":17},"Top third of subjects based levels of selected biomarker.",{"label":26,"type":17,"description":17,"interventionNames":17},"Middle third of subjects based levels of selected biomarker.",{"label":28,"type":17,"description":17,"interventionNames":17},"Bottom third ofsubjects based levels of selected biomarker.",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":17,"email":34},"Yuan Wang, PhD","CONTACT","86-010-64456721","wangyuan980510@163.com",{"name":36,"role":32,"phone":37,"phoneExt":17,"email":38},"Xue Wang, MD","+86 010-64456721","snowlove_@126.com",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Beijing Anzhen Hospital","RECRUITING","Beijing","Beijing Municipality","100029","China","CN",{"type":49,"coordinates":50},"Point",[51,52],116.39723,39.9075,{"lat":52,"lon":51},[55,58],{"name":56,"role":32,"phone":57,"phoneExt":17,"email":34},"Yuan WANG, PhD","86-010-64456169",{"name":59,"role":60,"phone":17,"phoneExt":17,"email":17},"Jie DU, PhD","PRINCIPAL_INVESTIGATOR",{"type":62,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR",[64,66,68,70,72,74],{"name":65,"class":6},"Beijing Luhe Hospital",{"name":67,"class":6},"The First Affiliated Hospital of Dalian Medical University",{"name":69,"class":6},"The First Hospital of Jilin University",{"name":71,"class":6},"First Affiliated Hospital, Sun Yat-Sen University",{"name":73,"class":6},"The General Hospital of Northern Theater Command",{"name":75,"class":6},"The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School","100303662",false,"NCT03233087","Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study","Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen","Inclusion Criteria:\n\nRetrospective\n\n* All patients who were referred to the surgical service for evaluation and management of aortic dissection were included.\n\nPerspective\n\n* Patients with initial suspicion of having AAD were perspectively enrolled.\n\nExclusion Criteria:\n\nRetrospective\n\n* Patients who received packed red blood cells, whole blood, or platelets less than 10 days before the blood sample was taken;\n* Patients with aortic trauma, pseudo aneurysm, history of heart failure, renal dysfunction, severe pulmonary diseases, or active cancer;\n* Patients who entered the hospital for checkups after surgery.\n\nPerspective\n\n* Patients in whom there is little or no suspicion of a life-threatening disease;\n* Patients with confirmed acute myocardial infarction,angina or pulmonary embolism\n* The symptoms were clearly not related to AD (e.g. pleurisy, pneumonia, acute abdominal diseases).","ALL","18 Years","80 Years",{"count":86,"type":87},1500,"ESTIMATED","OBSERVATIONAL","The registry study aims to determine serial biomarkers to diagnosis and prognosis of aortic aneurysm\u002Faortic dissection.",[91,92],"Aortic Aneurysm","Aortic Dissection","2024-06-26",{"date":95,"type":96},"2024-06-27","ACTUAL",{"date":98,"type":96},"2014-03-01",{"date":100,"type":87},"2028-12-31",{"name":5,"class":6},1]