Diet-Induced Changes in GEnetic Material
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age20-35
SponsorPennington Biomedical Research Center
About this trial
This is a pilot study in 10 men to test the hypothesis that perturbations in substrate flux and the circulating metabolic and pro-inflammatory milieus during a high-fat diet paradigm will modulate DNA methylation of genes in sperm associated with obesity and cardiometabolic dysfunction.
Eligibility criteria
Qualifiers
Male based on biological sex
Age 20-35 years
BMI between 18.5 and 24.9 kg/m2
White/Caucasian
Disqualifiers
Unstable weight in the last 3 months (±5% weight loss or gain)
Shift work or working in a factory setting
Habitual smoking or use of tobacco products, including vaping, within the past 6 months.
History of clinically diagnosed diabetes
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Locations
1Pennington Biomedical Research Center70808, Baton RougeLouisiana, United States
Sponsors and collaborators
Pennington Biomedical Research Center
Lead sponsor
Source ClinicalTrials.gov