[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606656":3},{"organization":4,"outcomesModule":7,"designInfo":65,"detailedDescription":67,"studyPopulation":68,"armGroups":69,"interventions":64,"overallOfficials":64,"centralContacts":72,"locations":80,"responsibleParty":97,"collaborators":99,"id":108,"slug":64,"hasResults":109,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":64,"eligibilityCriteria":113,"healthyVolunteers":109,"sex":114,"minAge":115,"maxAge":64,"enrollmentInfo":116,"targetDuration":64,"studyType":119,"phases":64,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":128,"whyStopped":64,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":138},{"fullName":5,"class":6},"Henan University of Traditional Chinese Medicine","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":64,"otherOutcomes":64},[9,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61],{"measure":10,"description":11,"timeFrame":12},"Disease Stage","Recording the disease staging of IPF patients. According to the Adult Idiopathic Pulmonary Fibrosis (Revised Edition) and Progressive Pulmonary Fibrosis: ATS\u002FERS\u002FJRS\u002FALAT Official Clinical Practice Guidelines (2022 Edition), and the Chinese Expert Consensus on the Diagnosis and Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis, the disease staging evaluation of IPF is stable phase or acute exacerbation.","Evaluate at baseline.",{"measure":14,"description":15,"timeFrame":12},"Gender, age and physiologic variables (GAP)stage","Recording the GAP stage of IPF patients. GAP stage is a risk stratification method that quantifies the three core parameters of patients: gender, age, and physiological parameters, by calculating the total score and conducting risk stratification.",{"measure":17,"description":18,"timeFrame":12},"Pulmonary function classification","Recording the pulmonary function classification of IPF patients. According to The Expert Consensus on the Diagnostic Criteria for Adult Lung Function in China, pulmonary function classification is divided into mild, moderate, and severe grades.",{"measure":20,"description":21,"timeFrame":12},"Natural course","Recording the natural course of IPF patient. According to international research, the natural course of IPF can be divided into stable, slow progression, rapid progression, and recurrent acute exacerbation. The specific criteria are as follows: 1.stable: FVC annual decline\\\u003C0.13L; 2. stable slow progression: FVC annual decline 0.13L-0.21L; 3. Rapid progress: FVC annual decline\\>0.21L; 4. Recurrent acute exacerbations: Annual number of acute exacerbations ≥ 1.",{"measure":23,"description":24,"timeFrame":12},"The Traditional Chinese Medicine(TCM) Syndromes","Evaluate traditional Chinese medicine syndromes by collecting patients' symptoms, signs, and tongue pulse information.",{"measure":26,"description":27,"timeFrame":12},"6 Six Minute Walk Distance(6MWD)","6MWD will be applied to evaluate the exercise capacity. The higher values indicate the better exercise capacity.",{"measure":29,"description":30,"timeFrame":12},"The 30 - second sit - to - stand test(30s STS)","The 30 second sitting and standing test will be used to evaluate lower limb strength and cardiopulmonary function.",{"measure":32,"description":33,"timeFrame":12},"A Tool to Assess Quality of life (ATAQ-IPF) total scores","ATAQ-IPF is currently a specialized scale for evaluating the quality of life, consisting of 13 dimensions and 74 items, with each item scored on a 1-5 scale. The higher the score, the worse the quality of life.",{"measure":35,"description":36,"timeFrame":12},"St. George's respiratory questionnaire (SGRQ) total scores","SGRQ is a scale used to evaluate the quality of life of patients, which includes three dimensions: symptoms, mobility, and the impact of disease on daily life, with a total of 50 items. The total score range of SGRQ is usually between 0 and 100, with higher scores leading to poorer quality of life.",{"measure":38,"description":39,"timeFrame":12},"Dyspnea","Dyspnea will be assessed by modified Medical Research Council(mMRC) scores. A score of 0-4 will be givenaccording to the degree of immediate dyspnea. A higher score indicates a worse condition.",{"measure":41,"description":42,"timeFrame":12},"C-reactive protein (CRP)","The CRP level will be detected by ELISA technology.",{"measure":44,"description":45,"timeFrame":12},"Krebs Von den Lungen-6（KL-6）","The KL-6 level will be detected by ELISA technology.",{"measure":47,"description":48,"timeFrame":12},"The pulmonary artery systolic pressure(PASP)","The PASP will be measured byechocardiogram.",{"measure":50,"description":51,"timeFrame":12},"The diameter of the pulmonary artery","The diameter of the pulmonary artery will be measured byechocardiogram.",{"measure":53,"description":54,"timeFrame":12},"Forced vital capacity (FVC)","FVC will be applied to assess pulmonary function.",{"measure":56,"description":57,"timeFrame":12},"FVC as the percentage of the predicted value (FVC%)","FVC% will be applied to assess pulmonary function.",{"measure":59,"description":60,"timeFrame":12},"Diffusing capacity of the lungs for carbon monoxide (DLCO)","DLCO will be applied to assess pulmonary function.",{"measure":62,"description":63,"timeFrame":12},"DLCO as the percentage of the predicted value (DLCO%)","DLCO% will be applied to assess pulmonary function.",null,{"allocation":64,"interventionModel":64,"interventionModelDescription":64,"primaryPurpose":64,"observationalModel":6,"timePerspective":66,"maskingInfo":64},"CROSS_SECTIONAL","This study, based on previous registration records, uses a cross-sectional survey design to collect demographic information, disease-related data, syndrome data, and auxiliary examination data from 2864 IPF patients in China. It aims to elucidate the syndrome types, disease characteristics, and the interrelationships between them of IPF at different stages, grades, and in its natural course.","Idiopathic pulmonary fibrosis (IPF) is a special type of idiopathic interstitial pneumonia, which is mainly manifested by irritating dry cough and progressive dyspnea.",[70],{"label":71,"type":64,"description":71,"interventionNames":64},"Participants fill out the questionnaire",[73,78],{"name":74,"role":75,"phone":76,"phoneExt":64,"email":77},"xueqing yu, Ph.D","CONTACT","+8613525518843","yxqshi@163.com",{"name":79,"role":75,"phone":64,"phoneExt":64,"email":64},"jiansheng li, Professor",[81],{"facility":82,"status":64,"city":83,"state":84,"zip":85,"country":86,"countryCode":87,"cosmosGeoPoint":88,"geoPoint":93,"contacts":94},"The First Affiliated Hospital of Henan University of Chinese Medicine","Zhengzhou","Henan","450000","China","CN",{"type":89,"coordinates":90},"Point",[91,92],113.64861,34.75778,{"lat":92,"lon":91},[95],{"name":96,"role":75,"phone":76,"phoneExt":64,"email":77},"xueqing yu",{"type":98,"investigatorFullName":64,"investigatorTitle":64,"investigatorAffiliation":64,"oldNameTitle":64,"oldOrganization":64},"SPONSOR",[100,102,104,106],{"name":101,"class":6},"The First Affiliated Hospital of Henan University of Traditional Chinese Medicine",{"name":103,"class":6},"China-Japan Friendship Hospital",{"name":105,"class":6},"The First Affiliated Hospital of Zhengzhou University",{"name":107,"class":6},"Shanghai Pulmonary Hospital, Shanghai, China","100606656",false,"NCT07178392","Disease-syndrome Characteristics of IPF","Research on the Disease-syndrome Characteristics of Idiopathic Pulmonary Fibrosis","Inclusion Criteria:\n\n1. Patients diagnosed with IPF;\n2. Age ≥ 18 years old;\n3. Voluntarily participate in this study and sign an informed consent form.\n\nExclusion Criteria:\n\n1. Patients with confusion, dementia, consciousness disorders, and various mental illnesses;\n2. Those who are unable to take care of themselves and have been bedridden for a long time.","ALL","18 Years",{"count":117,"type":118},2864,"ESTIMATED","OBSERVATIONAL","This study, based on previous registration records, aims to explore the syndrome patterns, disease characteristics, and their interrelationships of IPF at different stages, grades, and in its natural course, thus providing a multidimensional interpretation of the syndrome patterns and characteristics of IPF.",[122],"Idiopathic Pulmonary Fibrosis (IPF)",[124,125,126,127],"Idiopathic Pulmonary Fibrosis","TCM","Epidemiological investigation","characteristics","NOT_YET_RECRUITING","2025-09-10",{"date":131,"type":132},"2025-09-17","ACTUAL",{"date":134,"type":118},"2025-09-15",{"date":136,"type":118},"2028-11-30",{"name":5,"class":6},1]