Domain-Specific Large Language Model Assistance for Emergency Neurological Diagnosis and Treatment(DEMAND)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCapital Medical University

About this trial

This study will evaluate whether Xuanwu-NeuroAid 2.0, a large language model for emergency neurology, can improve 30-day diagnostic quality in adults with acute neurological symptoms. Physicians will be randomly assigned to AI-assisted care or usual care. In the AI-assisted group, the model will provide diagnostic and management suggestions, while physicians will make all final clinical decisions. The usual-care group will receive standard emergency neurology care without large language model assistance.

Eligibility criteria

Qualifiers

Age ≥18 years;

Presentation to the emergency neurology service with acute neurological symptoms;

Written informed consent provided by the patient or a legally authorized representative.

Disqualifiers

Presentation primarily for trauma;

Pregnancy;

Requiring immediate life-saving interventions;

Estimated life expectancy of less than 30 days;

Trial design

Treatments tested in this trial

  • Xuanwu-NeuroAid 2.0

Treatment groups

1,360 Participants
are divided into 2 treatment groups

Locations

3
Nanyang Nanshi Hospital473000, NanyangHenan, China
Liuyang Jili Hospital410300, GuankouHunan, China
Xuanwu Hospital,Capital Medical University100053, Beijing China

Sponsors and collaborators

Capital Medical University

Lead sponsor