[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574338":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":48,"collaborators":25,"id":52,"slug":25,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":25,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":25,"overallStatus":71,"whyStopped":25,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CTGT group","EXPERIMENTAL","a clinically guided resuscitation protocol, derived from EGDT",[13],"Procedure: a clinically guided resuscitation protocol,",{"label":15,"type":10,"description":16,"interventionNames":17},"ECHO group","a transthoracic bedside focused echocardiographic assessment of the patient",[18],"Procedure: a transthoracic bedside focused echocardiographic assessment",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","a clinically guided resuscitation protocol,","a clinically guided resuscitation protocol, derived from EGDT and modified to match with the latest survival sepsis campaign guidelines",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"a transthoracic bedside focused echocardiographic assessment","a transthoracic bedside focused echocardiographic assessment of the patient will be done, as a baseline ECHO in a three-step approach to monitor hemodynamics using Logiq P7, S5-1 ECHO probe;",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Ghada Abo Elfadl, MD","CONTACT","01005802086","ghadafadl77@gmail.com",[37],{"facility":38,"status":25,"city":39,"state":25,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":25},"woman health hospital , Assiut university","Asyut","71515","Egypt",{"type":43,"coordinates":44},"Point",[45,46],31.18368,27.18096,{"lat":46,"lon":45},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ghada Mohammed AboelFadl","Principal investigator","100574338",false,"NCT06757985","Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock.","Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock, a Randomized Controlled Trial","Inclusion Criteria:\n\n* postpartum women, within 6 weeks following delivery\n* meeting the third international consensus definitions for septic Shock (2016) (Sepsis-3): acute persisting hypotension requiring vasopressors to maintain mean arterial pressure (MAP) ≥ 65 mm Hg and having a serum lactate \\> 2 mmol\u002FL (18 mg\u002FdL) despite adequate volume resuscitation\n\nExclusion Criteria:\n\n* Patient refusal\n* History of any chronic cardiac disease\n* Requirement for immediate surgery\n* Hypotension attributable to another cause\n* Do-not-resuscitate status\n* Contraindication to central venous catheter placement\n* Difficult transthoracic echocardiographic evaluation\n* Primary cardiogenic cause of shock, instead of sepsis.","FEMALE","18 Years","45 Years",{"count":62,"type":63},60,"ESTIMATED","INTERVENTIONAL",[66],"NA","Postpartum sepsis is widely known as a preventable main cause of maternal morbidity and mortality. According to the World Health Organization, approximately 11% of the estimated maternal deaths worldwide were attributed to sepsis. Recent global assessments indicate that obstetric infections rank as the third most prevalent cause of maternal death, with a prevalence mainly observed in low- and middle-income nations.",[69,70],"Doppler Echocardiography","Postpartum Septic Shock","NOT_YET_RECRUITING","2025-01-03",{"date":74,"type":75},"2025-01-06","ACTUAL",{"date":77,"type":63},"2024-12-30",{"date":79,"type":63},"2026-11-30",{"name":5,"class":6},1]