[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644979":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":34,"responsibleParty":64,"collaborators":67,"id":70,"slug":20,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":20,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":94,"whyStopped":20,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Duodenal-jejunal bypass sleeve (DJBS)","EXPERIMENTAL","3 months implantation of DJBS",[13],"Procedure: Implantation of duodenal-jejunal bypass sleeve",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Implantation of duodenal-jejunal bypass sleeve","The duodenal-jejunal bypass sleeve (DJBS) is a 60 cm thin, flexible tube. It is implanted into the duodenum using an endoscopy procedure and is kept in place for 3 months. After 3 months, it will be removed endoscopically.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Stephen Ng, FRCSEd","Prince of Wales Hospital, the Chinese University of Hong Kong","PRINCIPAL_INVESTIGATOR",[27,31],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},"CONTACT","+85235052956","stephenng@surgery.cuhk.edu.hk",{"name":32,"role":28,"phone":20,"phoneExt":20,"email":33},"Ivy Study coordinator","ivypoon@surgery.cuhk.edu.hk",[35,53],{"facility":5,"status":20,"city":36,"state":20,"zip":20,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Shatin","Hong Kong",{"type":39,"coordinates":40},"Point",[41,42],114.18333,22.38333,{"lat":42,"lon":41},[45,46,47,48,51],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},{"name":32,"role":28,"phone":29,"phoneExt":20,"email":33},{"name":23,"role":25,"phone":20,"phoneExt":20,"email":20},{"name":49,"role":50,"phone":20,"phoneExt":20,"email":20},"Alice Kong, MD","SUB_INVESTIGATOR",{"name":52,"role":50,"phone":20,"phoneExt":20,"email":20},"Derek Xia, PhD",{"facility":54,"status":20,"city":36,"state":20,"zip":20,"country":37,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"CUHK Medical Centre",{"type":39,"coordinates":56},[41,42],{"lat":42,"lon":41},[59,63],{"name":60,"role":28,"phone":61,"phoneExt":20,"email":62},"Simon Wong, FRCSEd","+85239466888","wongkhmo@cuhk.edu.hk",{"name":60,"role":50,"phone":20,"phoneExt":20,"email":20},{"type":25,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Stephen KK Ng","Principal Investigator",[68],{"name":54,"class":69},"UNKNOWN","100644979",false,"NCT07675122","Duodenal-jejunal Bypass Sleeve (DJBS) for Obesity and Metabolic Syndrome","Endoscopic Duodenal-jejunal Bypass Sleeve for Treatment of Obesity and Metabolic Syndrome - a Multicenter Pilot Study","DJBS-OMS","Inclusion Criteria:\n\n* Body mass index (BMI) ≥27.5kg\u002Fm2; or BMI ≥25 kg\u002Fm2 with metabolic syndrome\n\nExclusion Criteria:\n\n* Patients who have lost more than 5 kg of weight in the past three months\n* Patients who have used glucagon-like peptide-1 receptor agonists (GLP-1RAs) in the past three months\n* Patients who are currently taking weight loss drugs such as orlistat\n* Those who have taken antiplatelet drugs or anticoagulant drugs such as aspirin in the past month\n* iron deficiency or iron deficiency anemia\n* Gastrointestinal malformations, such as patients with gastrointestinal atresia or other patients who will cause gastrointestinal implantation failure\n* Those with a history of cholecystitis and liver abscess\n* There is a known infection, and the type of disease and the severity of the infection are not suitable for use by clinicians\n* coagulation dysfunction;\n* Severe liver and kidney dysfunction, AST \u002FALT \\> 2.5 times, total bilirubin \\> 35 μmol\u002FL, blood creatinine concentration greater than 180 μmol\u002FL\n* Patients with ASA IV \\& V\n* Drug or alcohol abuse addiction or suffering from uncontrollable mental illness\n* Duodenal bulb ulcer, gastric ulcer or previous and existing pancreatitis\n* Coronary heart disease, angina, cardiac function grade III or above, or pulmonary dysfunction\n* Patients who have undergone ERCP before\n* Patients with potential bleeding or telangiectasia in the stomach, esophagus, small intestine and other parts\n* Have a history of systemic lupus erythematosus, scleroderma\n* Those who have contraindications to endoscopy (judged by clinicians)\n* Pregnant women or those who are preparing to become pregnant\n* Those who are allergic to nickel-titanium\n* Any other situation that the clinician deems unsuitable for participation in this product","ALL","18 Years","65 Years",{"count":81,"type":82},20,"ESTIMATED","INTERVENTIONAL",[85],"NA","This study is designed to evaluate the efficacy, safety, and mechanisms of duodenal-jejunal bypass sleeve in patients with obesity",[88,89],"Obesity","Metabolic Syndrome (MetS)",[91,92,93],"duodenal-jejunal bypass sleeve","DJBS","DJBL","NOT_YET_RECRUITING","2026-06-25",{"date":97,"type":98},"2026-06-30","ACTUAL",{"date":100,"type":82},"2026-08-01",{"date":102,"type":82},"2029-07-31",{"name":5,"class":6},2]