About this trial

Research has shown that timely suctioning not only improves survival rates but also enhances the quality of life in ventilator-dependent patients. However, clinical judgment on the optimal timing for suctioning currently relies primarily on physician experience, lacking scientific evidence \[10\]. Airway viscous resistance reflects the frictional resistance encountered by gas flow within the airways and is closely associated with airway patency. When airway secretions increase, viscous resistance undergoes dynamic changes. Therefore, analyzing these dynamic variations in viscous resistance derived from ventilator waveforms to determine the optimal suctioning timing and assess its clinical impact on the progression of pulmonary inflammation holds significant scientific value and offers new insights and methodologies for clinical practice.

Eligibility criteria

Qualifiers

Clinical diagnosis of Acute Respiratory Distress Syndrome (ARDS)

Clinical diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)

Clinical diagnosis of Severe pneumonia

Disqualifiers

Clinical diagnosis of multiple organ failure;

Clinical diagnosis of multiple organ bleeding;

Trial design

Treatments tested in this trial

  • The dynamics of airway resistance
  • conventional suctioning

Treatment groups

258 Participants
are divided into 2 treatment groups

Locations

3
The First Affiliated Hospital of Bengbu Medical University233000, BengbuAnhui, China
Peking Union Medical College Hospital100000, BeijingBeijing Municipality, China
the Second Affiliated Hospital of Zhejiang University School of Medicine310009, HangzhouZhejiang, China

Sponsors and collaborators

Affiliated Hospital of Nantong University

Lead sponsor