[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524514":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":18,"responsibleParty":37,"collaborators":18,"id":40,"slug":18,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":18,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":64,"whyStopped":18,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":18},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ACUMEN guided resuscitation protocol","EXPERIMENTAL","Fluid resuscitation and hemodynamic management will be guided by ACUMEN based off a protocol.",[13],"Other: Goal Directed Fluid Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care resuscitation","NO_INTERVENTION","Fluid resuscitation will be guided by standard monitors (urine output, blood loss, transesophageal echocardiography).",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Goal Directed Fluid Therapy","Fluid administration and hemodynamic management guided with the assistance of Edwards Lifesciences ACUMEN monitor",[9],[25],{"name":26,"affiliation":5,"role":27},"Reney A Henderson, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","4103283961","rhenderson@som.umaryland.edu",{"name":34,"role":30,"phone":35,"phoneExt":18,"email":36},"LaToya Stubbs","4103289951","lstubbs@som.umaryland.edu",{"type":27,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Reney Henderson","Assistant Professor","100524514",false,"NCT06109714","Early Biomarker Kidney Injury Assessment After Acumen Directed Fluid Management in Cardiac Surgery","BE-KIND","Inclusion Criteria:\n\n* Adult patients undergoing cardiopulmonary bypass\n* Procedure coronary artery bypass grafting, aortic valve replacement, or both\n\nExclusion Criteria:\n\n* Patients \\\u003C 18 years old\n* Emergent surgery\n* Preoperative kidney disease (Cr \\> 2.0 or on renal replacement therapy)\n* Ejection fraction \\\u003C 40%\n* Incomplete data in medical record",true,"ALL","18 Years","90 Years",{"count":51,"type":52},100,"ESTIMATED","INTERVENTIONAL",[55],"NA","This study is to assess the benefits of goal-directed fluid management with ACUMEN in cardiac surgical patients and its impact on cardiac surgery-induced kidney injury.",[58,59],"Renal Injury","Acute Kidney Injury",[61,62,63],"Cardiac Surgery","Cardiac Surgery Induced Kidney Injury","Kidney Biomarkers","NOT_YET_RECRUITING","2026-06-19",{"date":67,"type":68},"2026-06-23","ACTUAL",{"date":70,"type":52},"2026-09-01",{"date":72,"type":52},"2030-12-31",{"name":5,"class":6}]