[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641778":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":48,"collaborators":10,"id":51,"slug":10,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Odense University Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Total Hip Arthroplasty",null,"Patients aged 70 years or older undergoing elective unilateral total hip arthroplasty with planned discharge on the day of surgery.",{"label":13,"type":10,"description":14,"interventionNames":10},"Total Knee Arthroplasty","Patients aged 70 years or older undergoing elective unilateral total knee arthroplasty with planned discharge on the day of surgery.",{"label":16,"type":10,"description":17,"interventionNames":10},"Unicompartmental Knee Arthroplasty","Patients aged 70 years or older undergoing elective unilateral unicompartmental knee arthroplasty with planned discharge on the day of surgery.",[19],{"name":20,"affiliation":21,"role":22},"Martin Lindberg-Larsen, Professor","Head of Research \u002F Consultant Orthopaedic Surgeon at Odense University Hospital. Department of Clinical Research, University of Southern Denmark (SDU)","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Abdullahi Abdirisak Hirsi, MD","CONTACT","+4553376575","abdullahi.abdirisak.hirsi2@rsyd.dk",[30],{"facility":31,"status":32,"city":33,"state":10,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Odense University Hospital, Svendborg Hospital","RECRUITING","Svendborg","5700","Denmark",{"type":37,"coordinates":38},"Point",[39,40],10.60677,55.05982,{"lat":40,"lon":39},[43,44,47],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":20,"role":26,"phone":45,"phoneExt":10,"email":46},"+4551435711","martin.lindberg-larsen@rsyd.dk",{"name":25,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":22,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Abdullahi Abdirisak Hirsi","Medical doctor","100641778",false,"NCT07598552","Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty","Early Cognitive Changes in Patients Aged 70 Years or Older After Same-day Discharge Hip and Knee Arthroplasty: A Prospective Cohort Study","Inclusion Criteria:\n\n* Unilateral elective primary Total Hip Arthroplasty, Total Knee Arthroplasty, or Unicompartmental Knee\n* Native Danish speaker\n* Spinal anesthesia\n\nExclusion Criteria:\n\n* Inability or unwillingness to provide informed consent\n* Inability to comply with virtual study procedures or follow-up sessions, including because of visual or hearing impairment\n* Known dementia or other diagnosed cognitive disorders or Brief Assessment of Impaired Cognition (BASIC)≤20\n* Parkinson's disease or other neurological conditions causing functional impairment\n* History of alcohol abuse (≥35 units per week)\n* Daily use of anxiolytics or hypnotics\n* Not discharged on the day of surgery","ALL","70 Years",{"count":60,"type":61},48,"ESTIMATED","7 Days","OBSERVATIONAL","The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery. The main question it aims to answer is:\n\nDoes patients experience cognitive changes in cognitive test performance from before surgery to the first day after surgery?\n\nParticipants will:\n\n* Complete a cognitive test battery virtually about 14 days before surgery, and on the first and seventh day after their operation.\n* Record pain levels and pain medicine use during the first week after surgery",[66,67,13,16],"Postoperative Cognitive Dysfunction (POCD)","Cognitive Change",[69,70,71,72,73,74,75,76,77,78,79],"Same-day discharge","Fast-track surgery","Hip arthroplasty","Knee arthroplasty","Unicompartmental knee arthroplasty","Cognitive function","SDMT","Stroop test","Verbal fluency","Older adults","recovery","2026-06-17",{"date":82,"type":83},"2026-06-22","ACTUAL",{"date":85,"type":83},"2026-05-18",{"date":87,"type":61},"2026-11-30",{"name":5,"class":6},1]