[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316407":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":49,"collaborators":52,"id":56,"slug":27,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":27,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":27,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":32,"whyStopped":27,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Sao Paulo","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Treatment group","Early high-dose corticosteroid and immunosuppressive therapy",[12],"Drug: Early high-dose corticosteroid and immunosuppressive therapy",[14],{"type":15,"name":10,"description":10,"armGroupLabels":16,"otherNames":17},"DRUG",[9],[9],[19],{"name":20,"affiliation":21,"role":22},"Joyce H Yamamoto, MD","University of Sao Paulo School of Medicine Ophthalmology","PRINCIPAL_INVESTIGATOR",[24],{"name":20,"role":25,"phone":26,"phoneExt":27,"email":28},"CONTACT","55-11-99266-6474",null,"joycehy@uol.com.br",[30],{"facility":31,"status":32,"city":33,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Hospital das Clinicas HCFMUSP, Faculdade de Medicina Universidade de Sao Paulo","RECRUITING","São Paulo","05403-000","Brazil",{"type":37,"coordinates":38},"Point",[39,40],-46.63611,-23.5475,{"lat":40,"lon":39},[43,46],{"name":44,"role":25,"phone":45,"phoneExt":27,"email":28},"Joyce Yamamoto, MD","11992666474",{"name":47,"role":25,"phone":27,"phoneExt":27,"email":48},"Marcelo M Lavezzo, MD","mmlavezzo@gmail.com",{"type":22,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"Joyce Hisae Yamamoto","Professor",[53],{"name":54,"class":55},"Fundação de Amparo à Pesquisa do Estado de São Paulo","OTHER_GOV","100316407",false,"NCT03399175","Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease","Influência de imunomodulação Precoce Influence of Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease: a Prospective Study","Inclusion criteria:\n\n\\- acute Vogt-Koyanagi-Harada disease\n\nExclusion criteria:\n\n* non collaborative patient\n* minimum one-year follow-up","ALL","10 Years","70 Years",{"count":66,"type":67},40,"ESTIMATED","INTERVENTIONAL",[70],"NA","This prospective study will include patients with Vogt-Koyanagi-Harada disease from disease onset, treated with early systemic high-dose corticosteroid and immunosuppressive therapy. Clinical and subclinical signs of disease activity added with electroretinogram exams, through predefined intervals, will be evaluated through a minimum 12-month follow-up.",[73],"Vogt Koyanagi Harada Disease",[75,76,77,78,79],"Vogt-Koyanagi-Harada disease","Immunosuppressive therapy","Indocyanine green angiography","Enhanced depth imaging optical coherence tomography","Electroretinogram","2026-05-01",{"date":82,"type":83},"2026-05-07","ACTUAL",{"date":85,"type":83},"2015-03-23",{"date":87,"type":67},"2028-12",{"name":5,"class":6},1]