[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493518":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":23,"responsibleParty":76,"collaborators":78,"id":85,"slug":7,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":7,"eligibilityCriteria":90,"healthyVolunteers":86,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":7,"studyType":97,"phases":7,"briefSummary":98,"conditions":99,"keywords":7,"overallStatus":26,"whyStopped":7,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Lund University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Early neurological prognostication with biomarkers, EEG and CT","Biomarker samples collected at 12, 24, 48 and 72 h after randomisation, CT and EEG performed as early as possible after 24 h post randomisation in patients still unconscious (defined as not awake and able to follow verbal commands)",[14],{"name":15,"affiliation":5,"role":16},"Niklas Nielsen, MD, PhD","STUDY_CHAIR",[18],{"name":19,"role":20,"phone":21,"phoneExt":7,"email":22},"Marion Moseby-Knappe, MD, PhD","CONTACT","00464671000","marion.moseby_knappe@med.lu.se",[24,41,53,65],{"facility":25,"status":26,"city":27,"state":7,"zip":7,"country":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"Helsinki Hospital","RECRUITING","Helsinki","Finland",{"type":30,"coordinates":31},"Point",[32,33],24.93545,60.16952,{"lat":33,"lon":32},[36,38],{"name":37,"role":20,"phone":7,"phoneExt":7,"email":7},"Markus Skrifvars, Prof",{"name":39,"role":40,"phone":7,"phoneExt":7,"email":7},"Marjaana Tiainen, MD, PhD","SUB_INVESTIGATOR",{"facility":42,"status":26,"city":43,"state":7,"zip":7,"country":44,"cosmosGeoPoint":45,"geoPoint":49,"contacts":50},"Charité University Hospital","Berlin","Germany",{"type":30,"coordinates":46},[47,48],13.41053,52.52437,{"lat":48,"lon":47},[51],{"name":52,"role":20,"phone":7,"phoneExt":7,"email":7},"Christoph Leithner, MD",{"facility":54,"status":26,"city":55,"state":7,"zip":7,"country":56,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Helsingborgs Hospital","Helsingborg","Sweden",{"type":30,"coordinates":58},[59,60],12.69437,56.04673,{"lat":60,"lon":59},[63],{"name":64,"role":20,"phone":7,"phoneExt":7,"email":7},"Niklas Nielsen, Prof",{"facility":66,"status":26,"city":67,"state":7,"zip":7,"country":56,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Skane University Hospital","Lund",{"type":30,"coordinates":69},[70,71],13.19321,55.70584,{"lat":71,"lon":70},[74],{"name":75,"role":20,"phone":7,"phoneExt":7,"email":7},"Josef Dankiewicz, MD, PhD",{"type":77,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[79,80,82,83],{"name":54,"class":6},{"name":81,"class":6},"University of Helsinki",{"name":66,"class":6},{"name":84,"class":6},"Charite University, Berlin, Germany","100493518",false,"NCT05706194","Early Neuroprognostication After OHCA","Early Neurological Prognostication of Outcome After Out-of-hospital Cardiac arrest-a STEPCARE Prospective Substudy","Inclusion Criteria:\n\nAdult cardiac arrest patients with an out-of-hospital cardiac arrest of non-traumatic cause treated at hospitals recruiting patients to the STEPCARE neuroprognostication substudy. Other inclusion criteria include:\n\n* a minimum of 20 minutes without chest compressions\n* Unconsciousness defined as not being able to obey verbal commands (FOUR-score motor response of \\\u003C4) or being intubated and sedated because of agitation after sustained ROSC\n* Eligible for intensive care without restrictions or limitations\n* Inclusion within 4 hours of ROSC\n\nExclusion Criteria:\n\n* On ECMO prior to randomisation\n* Pregnancy\n* Suspected or confirmed intracranial hemorrhage\n* Previously randomised in the STEPCARE trial\n* Patients with limitations in level-of-care due to for example generalized malignancy","ALL","18 Years","100 Years",{"count":95,"type":96},1000,"ESTIMATED","OBSERVATIONAL","This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier than the 72 h time-point recommended by guidelines today.",[100,101,102,103,104,105],"Cardiac Arrest","Neurological Outcome","EEG","CT","Brain Injuries","Biomarkers","2024-03-20",{"date":108,"type":109},"2024-03-21","ACTUAL",{"date":111,"type":109},"2023-10-01",{"date":113,"type":96},"2029-07-31",{"name":5,"class":6},4]