[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589991":3},{"organization":4,"outcomesModule":7,"designInfo":22,"detailedDescription":21,"studyPopulation":21,"armGroups":28,"interventions":35,"overallOfficials":21,"centralContacts":21,"locations":41,"responsibleParty":63,"collaborators":21,"id":66,"slug":21,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":21,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":72,"maxAge":21,"enrollmentInfo":73,"targetDuration":21,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":21,"overallStatus":82,"whyStopped":21,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Atlantic Health System","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":21},[9],{"measure":10,"description":11,"timeFrame":12},"Culprit lesion","Can NaF PET-CT within 14 days of a non-cardiogenic thromboembolic stroke identify the likely culprit plaque as a source of the stroke","Within 14 days of the stroke",[14,18],{"measure":15,"description":16,"timeFrame":17},"Recurrent stroke","Can NaF PET-CT within 14 days of a non-cardiogenic thromboembolic stroke predict the location of a future non-cardiogenic thromboembolic stroke","Within 1 year of imaging",{"measure":19,"description":20,"timeFrame":17},"Management change","Can NaF PET-CT within 14 days of a non-cardiogenic thromboembolic stroke alter patient management",null,{"allocation":23,"interventionModel":24,"interventionModelDescription":21,"primaryPurpose":25,"observationalModel":21,"timePerspective":21,"maskingInfo":26},"NA","SINGLE_GROUP","DIAGNOSTIC",{"masking":27,"maskingDescription":21,"whoMasked":21},"NONE",[29],{"label":30,"type":31,"description":32,"interventionNames":33},"Intervention - NaF PET","EXPERIMENTAL","Intervention\u002FExperimental Arm - non-cardiogenic thromboembolic stroke patients to undergo NaF PET-CT",[34],"Drug: NaF PET-CT",[36],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":21},"DRUG","NaF PET-CT","Following a non-cardiogenic thromboembolic stroke, patients will undergo NaF PET-CT imaging to identify the culprit plaque and any other vulnerable plaques at high risk for rupture",[30],[42],{"facility":43,"status":21,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Overlook Medical Center","Summit","New Jersey","07901","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-74.36468,40.71562,{"lat":53,"lon":52},[56,61],{"name":57,"role":58,"phone":59,"phoneExt":21,"email":60},"James Cassuto, MD, PhD","CONTACT","908-522-2337","james.cassuto@atlantichealth.org",{"name":57,"role":62,"phone":21,"phoneExt":21,"email":21},"PRINCIPAL_INVESTIGATOR",{"type":62,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"jcassuto","MD","100589991",false,"NCT06961604","A Novel Method for Determination of Thromboembolic Stroke Origin","Inclusion Criteria: 18 years of age or older with a non-cardiogenic thromboembolic stroke in the past 14 days.\n\nExclusion Criteria: Less than 18 years of age, any other kind of stroke, not clinically stable to undergo PET-CT","ALL","18 Years",{"count":74,"type":75},20,"ESTIMATED","INTERVENTIONAL",[78],"EARLY_PHASE1","Rupture of vulnerable carotid, vertebral, and intracranial arterial plaques results in thromboembolic stroke. Identification of these culprit lesions is an important component of post-stroke care. This study seeks to test the feasibility of NaF PET-CT to detect these plaques and alter patient care. Prior studies have shown a high degree of correlation between NaF PET+ lesions and high-risk plaque features on high resolution MRI, including mirocalcification, necrosis, and ulceration.",[81],"Thromboembolic Stroke","NOT_YET_RECRUITING","2025-05-06",{"date":85,"type":86},"2025-05-08","ACTUAL",{"date":88,"type":75},"2025-06-01",{"date":90,"type":75},"2026-05-31",{"name":5,"class":6},1]