Health Trials

About this trial

The purpose of this research is to assess whether the use of a topical cream with an active ingredient can reduce the amount of foot pain experienced in participants who have been diagnosed with Diabetic Peripheral Neuropathy (DPN) with minimal side effects or discomfort from use.

Eligibility criteria

Qualifiers

At least 3 toes per foot

Have otherwise intact feet.

Absence of any eczema, hyperkeratosis, scleroderma, or other dermatological conditions afflicting the area of Test Article administration that may interfere with absorption, particularly hyperhidrosis.

Must agree to apply the Test Article to painful areas of feet as directed by research personnel.

Disqualifiers

Younger than 25 and older than 75 years of age

Any dermatological condition(s) with the potential to disrupt skin integrity or alter sensory function of the feet.

Any open wounds, skin ulceration, infection, skin irritation (e.g., poison oak), history of eczema, trauma or burn (including sunburn) affecting the feet within 30 days.

Any recent medical history of surgery affecting the feet.

Trial design

Treatments tested in this trial

  • Capsaicin Palmitate
  • Placebo

Treatment groups

80 Participants
are divided into 2 treatment groups

Locations

1
Carilion Clinic24016, RoanokeVirginia, United States

Sponsors and collaborators

Carilion Clinic

Lead sponsor

Source ClinicalTrials.gov