Optic Nerve Head Strain in Non-glaucoma Subjects
ConditionGlaucoma
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age30-90
SponsorJohns Hopkins University
About this trial
Persons who do not have glaucoma will have pictures taken of the optic nerve with a standard camera before and 2 weeks after starting to take a daily glaucoma eye drop to lower eye pressure. These data will be used to compare to the same procedure performed with glaucoma patients to study how glaucoma injures the eye.
Eligibility criteria
Qualifiers
Adults who have no history of OAG
Have an ocular examination by a glaucoma specialist with no indications of OAG
Have normal optical coherence tomography findings in the retinal nerve fiber layer.
Over age 30 will be included from
Disqualifiers
in whom sitting in an upright position is impossible due to physical disability
with ocular media opacity, corneal scarring, cataract or vitreous hemorrhage, that does not allow adequate imaging resolution.
in whom keeping the eyes open during the imaging procedure is not possible or uncomfortable.
who cannot perform home tonometry accurately at certification
Trial design
Treatments tested in this trial
- Latanoprost (0.005%)
Treatment groups
30 Participants
are divided into 1 treatment groupLocations
1Johns Hopkins Hospital21287, BaltimoreMaryland, United States
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
National Eye Institute (NEI)
Collaborator
Source ClinicalTrials.gov