Health Trials

About this trial

The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.

Researchers will compare a training program of eccentric overload training and eccentric cycling training with a traditional training program of strength and cardio training in people with heart failure with reduced ejection fraction.

This study will be delivered in a cardiac rehabilitation setting.

Eligibility criteria

Qualifiers

HFrEF patients with ejection fraction <40%

Exercise intolerance (<85% of predicted VO2 peak)

clinically stable for > 6 weeks, optimal medical treatment for > 6 weeks

Disqualifiers

Contra indications for cardiac exercise rehabilitation as per consensus guidelines and recommendations

Musculoskeletal disorders that hamper (progression in) strength training

Non-stabilized acute coronary syndrome

Current acute heart failure (decompensation)

Trial design

Treatments tested in this trial

  • eccentric bike training
  • eccentric overload training
  • aerobic treadmill training
  • aerobic bike training
  • traditional dynamic strength training

Treatment groups

3 Participants
are divided into 2 treatment groups

Locations

1
UHAntwerp2850, Edegem Belgium

Sponsors and collaborators

University Hospital, Antwerp

Lead sponsor

Source ClinicalTrials.gov