About this trial

The goal of this clinical trial is to determine whether a plant-focused diet improves nutritional and health outcomes of malnourished adults undergoing peritoneal dialysis (PD). It will also learn about the safety of this diet in this population.

The main questions it aims to answer are:

1. Does a plant-focused diet improve nutritional status compared to a standard kidney diet in PD patients? 2. What changes occur in anthropometric, biochemical, and dietary measures over 6 months?

Researchers will compare the plant-focused diet to a standard-of-care renal diet to see which is more effective in improving nutrition in PD patients.

Participants will:

* Be randomly assigned to follow the plant-focused diet or the standard diet. * Be monitored for 6 months through in-person visits (aligned with their routine clinic appointments) and virtual check-ins via messages or calls. * Have their progress monitored for changes in outcomes such as nutrition, blood tests, kidney function, and quality of life.

Eligibility criteria

Qualifiers

Adult outpatients (>18 years old), attending HTCM PD clinic visits

Have undergone peritoneal dialysis for at least 6 months

Have a serum albumin level <40 g/L

Have a BMI of < 25 kg/m2

Disqualifiers

Have been hospitalized for the past 3 months

Have ongoing infection/sepsis

Has undergone surgery in the past 6 months

Have high inflammatory diseases, malignancy, or cancer

Trial design

Treatments tested in this trial

  • Plant-Focused Diet Counselling
  • Standard Renal Diet Counselling

Treatment groups

100 Participants
are divided into 2 treatment groups

Locations

1
Hospital Canselor Tuanku Muhriz UKM56000, CherasKuala Lumpur, Malaysia

Sponsors and collaborators

National University of Malaysia

Lead sponsor