[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627581":3},{"organization":4,"outcomesModule":7,"designInfo":40,"detailedDescription":39,"studyPopulation":39,"armGroups":48,"interventions":60,"overallOfficials":39,"centralContacts":68,"locations":74,"responsibleParty":91,"collaborators":39,"id":95,"slug":39,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":96,"sex":102,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":39,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":39,"overallStatus":77,"whyStopped":39,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":39},[9],{"measure":10,"description":11,"timeFrame":12},"PAED score","Measured using the Pediatric Anesthesia Emergence Delirium (PAED) scale. The PAED scale ranges from 0 to 20, with higher scores indicating more severe emergence delirium (worse outcome).","Within 30 minutes after recovery",[14,18,22,26,29,32,35],{"measure":15,"description":16,"timeFrame":17},"Induction time","Time from face mask placement to loss of eyelash reflex, measured in seconds.","Immediately after anesthesia induction",{"measure":19,"description":20,"timeFrame":21},"Recovery time","Time from discontinuation of sevoflurane to full recovery of consciousness, measured in minutes.","Immediately after anesthesia discontinuation",{"measure":23,"description":24,"timeFrame":25},"Minimum alveolar concentration (MAC)","Minimum alveolar concentration (MAC) values recorded during anesthesia maintenance.","Perioperatively",{"measure":27,"description":28,"timeFrame":25},"Respiratory depression","Incidence of respiratory depression recorded during the perioperative period.",{"measure":30,"description":31,"timeFrame":25},"Hypoxia","Incidence of hypoxia recorded during the perioperative period.",{"measure":33,"description":34,"timeFrame":25},"Cough","Incidence of cough recorded during the perioperative period.",{"measure":36,"description":37,"timeFrame":38},"Nausea and vomiting","Incidence of nausea and vomiting recorded during the postoperative recovery period.","Immediately after anesthesia until discharge",null,{"allocation":41,"interventionModel":42,"interventionModelDescription":39,"primaryPurpose":43,"observationalModel":39,"timePerspective":39,"maskingInfo":44},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":45,"maskingDescription":39,"whoMasked":46},"SINGLE",[47],"PARTICIPANT",[49,55],{"label":50,"type":51,"description":52,"interventionNames":53},"Sevoflurane 8% Group","ACTIVE_COMPARATOR","Participants received 8% sevoflurane inhalation for anesthesia induction via face mask.",[54],"Drug: Sevoflurane",{"label":56,"type":57,"description":58,"interventionNames":59},"Sevoflurane 6% Group","EXPERIMENTAL","Participants received 6% sevoflurane inhalation for anesthesia induction via face mask.",[54],[61],{"type":62,"name":63,"description":64,"armGroupLabels":65,"otherNames":66},"DRUG","Sevoflurane","Sevoflurane inhalation anesthesia was used for induction and maintenance of general anesthesia in pediatric patients undergoing minor ophthalmic surgery.",[56,50],[67],"Sevorane,Sevorane,Ultane",[69],{"name":70,"role":71,"phone":72,"phoneExt":39,"email":73},"Laiwen Lv, MSc.","CONTACT","13750440405","llw@jsiec.org",[75],{"facility":76,"status":77,"city":78,"state":79,"zip":80,"country":81,"countryCode":82,"cosmosGeoPoint":83,"geoPoint":88,"contacts":89},"Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong","RECRUITING","Shantou","Guangdong","515041","China","CN",{"type":84,"coordinates":85},"Point",[86,87],116.67876,23.35489,{"lat":87,"lon":86},[90],{"name":70,"role":71,"phone":72,"phoneExt":39,"email":73},{"type":92,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":39,"oldOrganization":39},"PRINCIPAL_INVESTIGATOR","Laiwen Lv","Principal Investigator","100627581",false,"NCT07450495","Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery","Effectiveness and Safety of 6% Versus 8% Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Minor Surgery: A Randomized Controlled Trial","SEVO-PED","Inclusion Criteria:\n\n* Children aged 1 to 6 years (12-72 months)\n* Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia\n* American Society of Anesthesiologists (ASA) physical status I\n* Assessed as suitable for inhalation anesthesia by anesthesiologists\n* Written informed consent obtained from parents or legal guardians\n\nExclusion Criteria:\n\n* ASA physical status II or higher\n* Known hepatic or renal dysfunction\n* Congenital heart disease\n* History of malignant hyperthermia\n* Known allergy to sevoflurane\n* History of asthma or severe respiratory disease\n* Upper respiratory tract infection within the past 4 weeks\n* Anticipated difficult airway\n* Refusal of participation by parents or legal guardians","ALL","1 Year","6 Years",{"count":106,"type":107},80,"ESTIMATED","INTERVENTIONAL",[110],"NA","This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.",[113],"Chalazion","2026-02-27",{"date":116,"type":117},"2026-03-04","ACTUAL",{"date":119,"type":117},"2025-02-25",{"date":121,"type":107},"2026-04-01",{"name":5,"class":6},1]