About this trial

This randomized controlled trial investigates the effect of electroacupuncture as an adjunct to local anesthesia on perioperative pain and stress during ambulatory surgical extraction of impacted lower third molars. Participants will be randomized into three groups: electroacupuncture, sham acupuncture, and control. Pain intensity and perceived stress will be assessed using validated scales, while biological stress and nociceptive markers (salivary cortisol, alpha-amylase, and substance P), as well as hemodynamic parameters (blood pressure and heart rate), will be measured. The study aims to provide an integrated evaluation of the effects of electroacupuncture on subjective, biological, and physiological indicators of perioperative response in oral surgery.

Eligibility criteria

Qualifiers

Adults aged 25-35 years

ASA physical status I-II

Indication for ambulatory surgical extraction of an impacted lower third molar

Ability to understand the study procedures and provide written informed consent

Disqualifiers

Pregnancy

Epilepsy

Presence of a pacemaker or other active electronic implant

Coagulation disorders

Trial design

Treatments tested in this trial

  • Electroacupuncture
  • Sham Acupuncture

Treatment groups

60 Participants
are divided into 3 treatment groups

Locations

1
University Hospital Dubrava10000, Zagreb Croatia

Sponsors and collaborators

University of Zagreb

Lead sponsor