About this trial
The main objective of the study is to assess whether a dietary regimen based on the principles of the FODMAP diet, compared with the current treatment programme which does not include specific dietary recommendations, can improve pain symptoms in patients with symptomatic endometriosis and intestinal symptoms (i.e. bloating, nausea, constipation, diarrhoea and vomiting) attributable to irritable bowel syndrome, compared with a control group
Eligibility criteria
Qualifiers
Age between 18 and 45 years
BMI between 18.5 and 24.9,
Surgical, clinical or instrumental diagnosis of endometriosis
Presence of bowel symptoms (i.e., bloating, nausea, constipation, diarrhea, and vomiting) referable to irritable bowel syndrome, on estro-progestin or progestin treatment or in the absence of hormonal treatment
Disqualifiers
Associated conditions that may cause pelvic pain independent of the presence of endometriosis (e.g., pelvic varices and salpingitis outcomes)
chronic inflammatory bowel disease (Crohn's disease or ulcerative rectocolitis).
patients with obstructive uropathy, subocclusive intestinal stenosis
complex adnexal masses or typical endometriomas greater than 5 cm in diameter.
Trial design
Treatments tested in this trial
- FODMAP diet
Treatment groups
Locations
1Sponsors and collaborators
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Lead sponsor