[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642545":3},{"organization":4,"outcomesModule":7,"designInfo":24,"detailedDescription":32,"studyPopulation":23,"armGroups":33,"interventions":45,"overallOfficials":23,"centralContacts":55,"locations":23,"responsibleParty":64,"collaborators":23,"id":68,"slug":23,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":23,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":23,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":23,"overallStatus":86,"whyStopped":23,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":23},{"fullName":5,"class":6},"Middle East University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":23},[9],{"measure":10,"description":11,"timeFrame":12},"Balance","Berg Balance Scale will be used to assess balance. A 14-item objective clinical rating scale evaluating functional balance performance (e.g., reaching, turning, standing on one leg). Scores range from 0 to 56, where higher scores indicate better balance control.","Baseline and after 8 weeks",[14,17,20],{"measure":15,"description":16,"timeFrame":12},"Health-Related Quality of Life","Multiple Sclerosis Quality of Life-54 Questionnaire will be used to assess quality of life. It is a multidimensional, disease-specific questionnaire combining generic and disease-specific items. It generates 12 subscales along with distinct physical and mental health composite summary scores. Higher scores indicate a better quality of life.",{"measure":18,"description":19,"timeFrame":12},"Risk of Fall","The Fall Risk Questionnaire will be used to assess the risk of fall. The Fall Risk Questionnaire consists of 12 yes\u002Fno questions. For scoring, a \"no\" answer is scored as zero for all questions, while a \"yes\" answer is scored as two for the first two questions and as one for the remaining 10 questions. A total Fall Risk Questionnaire score of 4 or higher indicates increased fall risk.",{"measure":21,"description":22,"timeFrame":12},"Core Muscle Function","The Trunk Impairment Scale will be used to assess core muscle function. It scores static sitting balance, dynamic sitting balance, and trunk coordination. Total scores range from 0 to 23, with higher scores indicating superior core control.",null,{"allocation":25,"interventionModel":26,"interventionModelDescription":23,"primaryPurpose":27,"observationalModel":23,"timePerspective":23,"maskingInfo":28},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":29,"maskingDescription":23,"whoMasked":30},"SINGLE",[31],"OUTCOMES_ASSESSOR","Patients diagnosed with multiple sclerosis will be recruited from outpatient neurology and physical therapy clinics. Following clinical screening, eligible participants will be randomly assigned into two parallel groups:\n\nThe Study Group: Will receive High-Intensity Focused Electromagnetic Therapy sessions targeted at the core\u002Ftrunk muscles plus a structured balance exercise program for 8 weeks.\n\nThe Control Group: Will receive the structured balance exercise program only for 8 weeks.",[34,41],{"label":35,"type":36,"description":37,"interventionNames":38},"Experimental group","ACTIVE_COMPARATOR","Patients with multiple sclerosis who will receive High-Intensity Focused Electromagnetic Therapy targeted at the abdominal and paraspinal core musculature, combined with a specialized balance training program for 8 weeks",[39,40],"Device: High-Intensity Focused Electromagnetic Therapy","Other: Balance Exercises",{"label":42,"type":36,"description":43,"interventionNames":44},"Control group","Patients with multiple sclerosis who will receive the standardized balance training program alone for 8 weeks.",[40],[46,51],{"type":47,"name":48,"description":49,"armGroupLabels":50,"otherNames":23},"DEVICE","High-Intensity Focused Electromagnetic Therapy","For 8 weeks, two weekly sessions of High-Intensity Focused Electromagnetic Therapy will be used to induce supramaximal contractions to strengthen the central core stabilizers (rectus abdominis, transversus abdominis, and erector spinae)",[35],{"type":6,"name":52,"description":53,"armGroupLabels":54,"otherNames":23},"Balance Exercises","Standardized balance training including static stance variations, dynamic weight-shifting, perturbation training, and functional gait adjustments will be conducted for 30-45 minutes per session through three weekly sessions for a total duration of 8 weeks.",[42,35],[56,61],{"name":57,"role":58,"phone":59,"phoneExt":23,"email":60},"Saher Lotfy Elgayar, Ph.D","CONTACT","+201020429911","saherlotfy020@gmail.com",{"name":62,"role":58,"phone":63,"phoneExt":23,"email":23},"Mohammed Youssef Elhamrawy, Ph.D","+201282805567",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Saher Lotfy El Gayar","Assistant Professor of Physiotherapy","100642545",false,"NCT07646912","Effect of High-Intensity Focused Electromagnetic Therapy on Balance and Quality of Life in Patients With Multiple Sclerosis","Effect of High-Intensity Focused Electromagnetic Technology on Balance and Quality of Life in Patients With Multiple Sclerosis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Confirmed clinical diagnosis of Multiple Sclerosis according to the revised McDonald criteria.\n* Expanded Disability Status Scale score range between 3.0 and 5.5.\n* Clinically stable condition with no neurological relapses or corticosteroid therapy within the past 3 months.\n\nExclusion Criteria:\n\n* Presence of pacemakers, internal defibrillators, or metallic implants in the torso\u002Fabdominal region.\n* Severe cognitive impairment interfering with the understanding of instructions or questionnaires.\n* Other concomitant neurological or musculoskeletal orthopedic conditions that independently affect balance or gait.\n* Severe visual deficits or uncorrected vestibular disorders.\n* Pregnancy.","ALL","18 Years","60 Years",{"count":78,"type":79},60,"ESTIMATED","INTERVENTIONAL",[82],"NA","Evaluate the effect of High-Intensity Focused Electromagnetic Therapy on dynamic balance, fall risk, core muscle function, and quality of life in patients with multiple sclerosis.",[85],"Multiple Sclerosis","NOT_YET_RECRUITING","2026-06-09",{"date":89,"type":90},"2026-06-15","ACTUAL",{"date":92,"type":79},"2026-06-22",{"date":94,"type":79},"2026-10-14",{"name":5,"class":6}]