[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546147":3},{"organization":4,"outcomesModule":7,"designInfo":28,"detailedDescription":11,"studyPopulation":31,"armGroups":11,"interventions":32,"overallOfficials":35,"centralContacts":39,"locations":11,"responsibleParty":44,"collaborators":11,"id":47,"slug":11,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":11,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":11,"enrollmentInfo":55,"targetDuration":11,"studyType":58,"phases":11,"briefSummary":59,"conditions":60,"keywords":11,"overallStatus":64,"whyStopped":11,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":11},{"fullName":5,"class":6},"Peking University First Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":16},[9],{"measure":10,"description":11,"timeFrame":12},"preterm birth rate",null,"10 months",[14],{"measure":15,"description":11,"timeFrame":12},"delivery methods",[17,19,22,25],{"measure":18,"description":11,"timeFrame":12},"pregnancy complications",{"measure":20,"description":21,"timeFrame":12},"neonatal birth weight","birth weight of newborns measured in grams",{"measure":23,"description":24,"timeFrame":12},"neonatal length","length of newborns measured in centimeters",{"measure":26,"description":27,"timeFrame":12},"Apgar score of newborns","The Apgar score consists of five main indicators: skin color, heart rate, response to stimulation, muscle tone, and respiration. Each indicator is scored from 0 to 2, with a total score of 10. This scoring method serves as a guiding tool for the resuscitation of newborns with asphyxia and could provide a degree of predictive value for the neurological development of infants in the future.",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":29,"timePerspective":30,"maskingInfo":11},"COHORT","PROSPECTIVE","Pregnant women who have established prenatal care records and undergone antenatal check-ups at PKUFH",[33],{"type":6,"name":34,"description":34,"armGroupLabels":11,"otherNames":11},"exposure: OSA resulting from chronic tonsillitis",[36],{"name":37,"affiliation":5,"role":38},"Xiaowan Du","STUDY_DIRECTOR",[40],{"name":37,"role":41,"phone":42,"phoneExt":11,"email":43},"CONTACT","13552834319","xiaowandu26@126.com",{"type":45,"investigatorFullName":37,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100546147",false,"NCT06391151","Effect of OSA Resulting From Chronic Tonsillitis on Pregnancy Outcomes","Effect of Obstructive Sleep Apnea (OSA) Resulting From Chronic Tonsillitis on Pregnancy Outcomes","Inclusion Criteria:\n\n* Pregnant women confirmed with chronic tonsillitis by clinical diagnosis and presenting symptoms.\n* Pregnant women with a confirmed diagnosis of OSA based on polysomnography or other validated sleep monitoring techniques.\n* Pregnant women who are willing to participate in the study and provide informed consent.\n\nExclusion Criteria:\n\n* Pregnant women with other respiratory or sleep disorders that may confound the diagnosis of OSA.\n* Pregnant women with severe comorbidities or medical conditions that may significantly impact pregnancy outcomes.\n* Pregnant women who have undergone surgical treatment for chronic tonsillitis or OSA during the study period.\n* Pregnant women who refuse to participate in the study or are unable to provide informed consent.","FEMALE","18 Years",{"count":56,"type":57},500,"ESTIMATED","OBSERVATIONAL","This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) resulting from chronic tonsillitis on pregnancy outcomes. The hypothesis posits that chronic tonsillitis-induced OSA may exacerbate pregnancy complications and increase the risk of adverse pregnancy outcomes.",[61,62,63],"Obstructive Sleep Apnea","Chronic Tonsillitis","Pregnancy","NOT_YET_RECRUITING","2024-06-03",{"date":67,"type":68},"2024-06-04","ACTUAL",{"date":70,"type":57},"2024-07-01",{"date":72,"type":57},"2026-06-30",{"name":5,"class":6}]