[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100345295":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":28,"studyPopulation":17,"armGroups":29,"interventions":42,"overallOfficials":48,"centralContacts":52,"locations":61,"responsibleParty":78,"collaborators":17,"id":80,"slug":17,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":17,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":17,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":17,"overallStatus":64,"whyStopped":17,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Pusan National University Yangsan Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":12,"otherOutcomes":17},[9],{"measure":10,"description":10,"timeFrame":11},"Alanine aminotransferase","8 weeks",[13,15],{"measure":14,"description":14,"timeFrame":11},"Aspartate aminotransferase",{"measure":16,"description":16,"timeFrame":11},"Gamma-glutamyl transferase",null,{"allocation":19,"interventionModel":20,"interventionModelDescription":17,"primaryPurpose":21,"observationalModel":17,"timePerspective":17,"maskingInfo":22},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":23,"maskingDescription":17,"whoMasked":24},"TRIPLE",[25,26,27],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","Previous studies have indicated that Panax Ginseng C.A. Mey Extract may have the ability to improve liver function. Therefore, the investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of the Panax Ginseng C.A. Mey Extract on liver function in adults; the safety of the compound are also evaluate. The Investigators examine AST, ALT, GGT, and other metabolic parameters at baseline, as well as after 4 and 8 weeks of intervention. Sixty adults were administered either 600 mg of Panax Ginseng C.A. Mey Extract or a placebo each day for 8 weeks;",[30,36],{"label":31,"type":32,"description":33,"interventionNames":34},"Panax Ginseng C.A. Mey Extract group","EXPERIMENTAL","This group takes Panax Ginseng C.A. Mey Extract for 8 weeks",[35],"Dietary Supplement: Panax Ginseng C.A. Mey Extract group",{"label":37,"type":38,"description":39,"interventionNames":40},"Placebo group","PLACEBO_COMPARATOR","This group takes placebo for 8 weeks",[41],"Dietary Supplement: Placebo group",[43,46],{"type":44,"name":31,"description":33,"armGroupLabels":45,"otherNames":17},"DIETARY_SUPPLEMENT",[31],{"type":44,"name":37,"description":39,"armGroupLabels":47,"otherNames":17},[37],[49],{"name":50,"affiliation":5,"role":51},"Sang Yeoup Lee","PRINCIPAL_INVESTIGATOR",[53,58],{"name":50,"role":54,"phone":55,"phoneExt":56,"email":57},"CONTACT","360-2860","055","saylee@pnu.edu",{"name":59,"role":54,"phone":55,"phoneExt":56,"email":60},"Ye Li Lee","yeri1230@gmail.com",[62],{"facility":63,"status":64,"city":65,"state":17,"zip":66,"country":67,"countryCode":17,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Integrated Research Institute for Natural Ingredients and Functional Foods","RECRUITING","Yangsan","50612","South Korea",{"type":69,"coordinates":70},"Point",[71,72],129.03358,35.34199,{"lat":72,"lon":71},[75],{"name":76,"role":54,"phone":77,"phoneExt":17,"email":57},"Sang Yeoup Lee, MD","82-55-360-2860",{"type":51,"investigatorFullName":50,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"Professor","100345295",false,"NCT03775837","Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults","Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults: a Randomized, Double-blinded, Placebo-controlled Trial","Inclusion Criteria:\n\n* ALT ranging from upper limit of reference to three times of upper limit\n\nExclusion Criteria:\n\n* Abnormal liver or renal function (i.e., serum aminotransferase activity \\> 3 times of upper limit of reference range and serum creatinine concentrations \\> 1.2 mg\u002FdL)\n* Diabetes (diagnosed clinically or fasting glucose level \\> 126 mg\u002FdL)\n* History of viral hepatitis or cancer\n* Uncontrolled hypertension\n* History of serious cardiac disease such as angina or myocardial infarction\n* History of gastrectomy\n* History of medication for psychiatric disease\n* Administration of oriental medicine including herbs within the past 4 weeks",true,"ALL","19 Years","75 Years",{"count":91,"type":92},60,"ESTIMATED","INTERVENTIONAL",[95],"NA","The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Panax Ginseng C.A. Mey Extract on liver function in adults for 8 weeks.",[98],"Liver Diseases","2025-06-01",{"date":101,"type":102},"2025-06-04","ACTUAL",{"date":104,"type":102},"2018-12-01",{"date":106,"type":92},"2025-12-31",{"name":5,"class":6},1]