[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556381":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":44,"locations":54,"responsibleParty":66,"collaborators":68,"id":72,"slug":26,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":26,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":97,"overallStatus":109,"whyStopped":26,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"GEM Hospital & Research Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pelvic Floor Physiotherapy (PFR) group","EXPERIMENTAL","Patients completing three months post-low anterior resection (LAR) for rectal cancer or six weeks post-diversion ileostomy closure following LAR will be recruited to Pelvic Floor Rehabilitation (PFR) group after randomization.\n\nIntervention: Participants will undergo a structured pelvic floor physiotherapy program for three months.\n\nThe program includes:\n\nEight Personal Sessions: Each session lasts 45 minutes.\n\nFrequency:\n\n* Once a week for the first month (four sessions).\n* Biweekly for the next two months (four sessions).\n\nHome Exercises: Participants will be guided on pelvic floor exercises to be performed at home throughout the three months.\n\nUsual Care: In addition to the pelvic floor rehabilitation, participants will receive the standard postoperative care for rectal cancer surgery.",[13],"Behavioral: Pelvic Floor Physiotherapy (PFR)",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional group","ACTIVE_COMPARATOR","Patients completing three months post-low anterior resection (LAR) for rectal cancer or six weeks post-diversion ileostomy closure following LAR will be recruited to Conventional group after randomization.\n\nRecruited subjects in the conventional group recieves usual care following low anterior resection such as fluid intake, fiber intake, diet, toilet posture, life style advice etc",[19],"Behavioral: Conventional group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Pelvic Floor Physiotherapy (PFR)","Intervention: Participants will undergo a structured pelvic floor physiotherapy program for three months.\n\nThe program includes:\n\nEight Personal Sessions: Each session lasts 45 minutes.\n\nFrequency:\n\nOnce a week for the first month (four sessions). Biweekly for the next two months (four sessions). Home Exercises: Participants will be guided on pelvic floor exercises to be performed at home throughout the three months.",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":28,"otherNames":26},[15],[30,34,37,40,42],{"name":31,"affiliation":32,"role":33},"Harshavardhana H P, MS DrNB (IP)","GEM Coimbatore","PRINCIPAL_INVESTIGATOR",{"name":35,"affiliation":32,"role":36},"RAJAPANDIAN S, DNB FRCS(Ed)","STUDY_DIRECTOR",{"name":38,"affiliation":32,"role":39},"PALANIVELU C, MS Mch FRCS","STUDY_CHAIR",{"name":41,"affiliation":32,"role":36},"HARISH KAKKILAYA, MS FACRSI",{"name":43,"affiliation":32,"role":36},"SHANKAR B, MS DrNB FRCS",[45,50],{"name":31,"role":46,"phone":47,"phoneExt":48,"email":49},"CONTACT","9113200790","91","Harshavardhanmmc@gmail.com",{"name":51,"role":46,"phone":52,"phoneExt":48,"email":53},"Rajapandian S, DNB FRCS(Ed)","9843026290","srajapandian@rediffmail.com",[55],{"facility":5,"status":26,"city":56,"state":57,"zip":58,"country":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":26},"Coimbatore","Tamil Nadu","641045","India",{"type":61,"coordinates":62},"Point",[63,64],76.96612,11.00555,{"lat":64,"lon":63},{"type":67,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[69],{"name":70,"class":71},"JOGO Health Pvt Ltd","UNKNOWN","100556381",false,"NCT06524362","Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial","Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial (PERECARE TRIAL)","PERECARE","Inclusion Criteria:\n\n* Age: Adults aged 18 years or older.\n* Surgical Procedure: Have undergone Low Anterior Resection (LAR) for rectal cancer.\n* Cognitive Ability: Capable of understanding and completing the questionnaires effectively\n\nExclusion Criteria:\n\n* Medical History: History of proctitis, ulcerative colitis, or Crohn's disease.\n* Surgical Extent: Extensive resection (beyond Total Mesorectal Excision - TME) for\n* locally advanced (T4) tumors, patients undergoing APR.\n* Surgical Complications: History of anastomotic leakage.\n* Recent Physiotherapy: History of invasive physiotherapy within the past 6 months.\n* Mental or Physical Inabilities: Inability to undergo Pelvic Floor Rehabilitation due to mental or physical limitations","ALL","18 Years","85 Years",{"count":83,"type":84},77,"ESTIMATED","INTERVENTIONAL",[87],"NA","Study Purpose:\n\nThis study aims to understand how pelvic floor rehabilitation (PFR) after low anterior resection (LAR) surgery for rectal cancer affects bowel control and quality of life compared to usual care.\n\nBackground:\n\nRectal cancer and its treatments can significantly impact patients' lives, often causing bowel issues like frequent bowel movements, urgency, and incontinence. These problems, known as low anterior resection syndrome (LARS), affect 70-90% of patients and can last for over two years. (1,2)\n\nCurrent Knowledge:\n\nAdvances in treatments have improved survival rates and recovery. Despite improvements, many patients still experience bowel issues after surgery.\n\nPast studies show PFR can help, but they have limitations like small sample sizes and varied methods. (3-5)\n\nNeed for the Study:\n\nThere is a need for a well-designed study to confirm the benefits of PFR and to identify which patients benefit the most.\n\nStudy Design:\n\nThis study is a randomized controlled trial that will:\n\n* Compare PFR to usual care in patients after LAR surgery.\n* Focus on bowel control and quality of life.\n* Provide detailed insights to improve aftercare for rectal cancer patients.",[90,91,92,93,94,95,96],"Rectal Cancer","Rectum Neoplasm","Rectal Neoplasms","Rectal Adenocarcinoma","Low Anterior Resection Syndrome","Fecal Incontinence","Bowel Dysfunction",[98,99,100,101,102,103,104,105,106,107,108],"Pelvic Floor Rehabilitation","Low Anterior Resection","Ultra Low Anterior Resection","Rectal Cancer Surgery","Post operative care","Bowel function","Quality of life","Randomized controlled trial","Fecal Urgency","Pelvic Floor Muscle Training","Oncological outcomes","NOT_YET_RECRUITING","2024-07-23",{"date":112,"type":113},"2024-07-29","ACTUAL",{"date":115,"type":84},"2024-08",{"date":117,"type":84},"2026-03",{"name":5,"class":6},1]