[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522431":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":11,"centralContacts":27,"locations":33,"responsibleParty":48,"collaborators":11,"id":50,"slug":11,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":11,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":11,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":71,"overallStatus":35,"whyStopped":11,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Xijing Hospital","OTHER",[8,12,18],{"label":9,"type":10,"description":11,"interventionNames":11},"Preoperative","NO_INTERVENTION",null,{"label":13,"type":14,"description":15,"interventionNames":16},"postoperative (6 weeks)","EXPERIMENTAL","The patients were injected with PRP.",[17],"Drug: Sodium hyaluronate injection",{"label":19,"type":14,"description":15,"interventionNames":20},"postoperative (3 months)",[17],[22],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"DRUG","Sodium hyaluronate injection","The control group was injected into the joint cavity with sodium hyaluronate injection..",[19,13],[28],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Yanyan Jia","CONTACT","+862984771794","xiyyllwyh@163.com",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Xi'an","Shannxi","710034","China",{"type":41,"coordinates":42},"Point",[43,44],108.92861,34.25833,{"lat":44,"lon":43},[47],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},{"type":49,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100522431",false,"NCT06082531","Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis","Therapeutic Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis and Periarticular Tissue Injury","Inclusion Criteria:\n\n* The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint.\n* The preoperative routine tests and examinations revealed no contraindications.\n* Revised sentence: \"Informed consent of the patient\n\nExclusion Criteria:\n\n* The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream.\n* Prolonged usage of anti-inflammatory drugs and systemic corticoid administration.\n* In injection site or damage to the skin.\n* Patients with tumors or undergoing radiotherapy and chemotherapy.\n* Pregnant or breastfeeding women.\n* Individuals with mental illnesses who are unable to cooperate with follow-up procedures.\n* Contraindications for MRI、Patients or their families do consent to participate in the study.\n* Other circumstances that render participation in the study unsuitable.","ALL","20 Years","60 Years",{"count":60,"type":61},300,"ESTIMATED","INTERVENTIONAL",[64],"NA","To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.",[67,68,69,70],"Platelets-rich Plasma","Osteoarthritis Knees Both","Meniscus Disorder","Cartilage Injury",[72,73,70,74],"platelets-rich plasma","Osteoarthritis","Meniscus Injury","2025-04-06",{"date":77,"type":78},"2025-04-09","ACTUAL",{"date":80,"type":78},"2023-09-01",{"date":82,"type":61},"2025-12-31",{"name":5,"class":6},1]