[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100537244":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":27,"locations":38,"responsibleParty":58,"collaborators":19,"id":61,"slug":19,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":19,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":19,"maxAge":68,"enrollmentInfo":69,"targetDuration":19,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":19,"overallStatus":41,"whyStopped":19,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observational Group","EXPERIMENTAL","Manipulation of end tidal carbon dioxide in subjects",[13],"Other: Ventilation manipulation",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Ventilation manipulation","Effects of ventilation manipulation to achieve desired levels of end tidal carbon dioxide",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Amy Monroe, MPH, MBA","STUDY_DIRECTOR",{"name":25,"affiliation":5,"role":26},"Kanwal Nischal, MD,FRCOphth","PRINCIPAL_INVESTIGATOR",[28,33],{"name":22,"role":29,"phone":30,"phoneExt":31,"email":32},"CONTACT","412-623-6382","6382","monroeal@upmc.edu",{"name":34,"role":29,"phone":35,"phoneExt":36,"email":37},"Alisha Maslanka, BS, CCRC","412-491-2748","2748","alisha.maslanka@chp.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"University of Pittsburgh Medical Center","RECRUITING","Pittsburgh","Pennsylvania","15224","United States",{"type":47,"coordinates":48},"Point",[49,50],-79.99589,40.44062,{"lat":50,"lon":49},[53,54,55],{"name":22,"role":29,"phone":19,"phoneExt":19,"email":32},{"name":25,"role":26,"phone":19,"phoneExt":19,"email":19},{"name":56,"role":57,"phone":19,"phoneExt":19,"email":19},"Lieu Tran, MD","SUB_INVESTIGATOR",{"type":26,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Kanwal Nischal","Professor","100537244",false,"NCT06275308","Effect of Raised End-Tidal pCo2 on Choroidal Volume","Inclusion Criteria:\n\n* any child undergoing an eye exam under anesthesia for an ophthalmologic reason.\n* children between the ages newborn to 8 years of age.\n\nExclusion Criteria:\n\n* children who are not having an eye exam under anesthesia.\n* children with a known medical diagnosis that affect the eye to be studied\n* \\* children over the age of 8 years of age.\n* \\* children with altered cerebral autoregulation, increased intracranial pressure, pulmonary hypertension, or any other condition deemed appropriate by the anesthesiologist.\n* children in whom a laryngeal mask airway will not be used",true,"ALL","8 Years",{"count":70,"type":71},20,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.",[77],"Intraocular Pressure","2026-01-07",{"date":80,"type":81},"2026-01-09","ACTUAL",{"date":83,"type":81},"2023-02-27",{"date":85,"type":71},"2026-12-30",{"name":5,"class":6},1]