[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484989":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":16,"studyPopulation":16,"armGroups":29,"interventions":39,"overallOfficials":16,"centralContacts":16,"locations":44,"responsibleParty":65,"collaborators":16,"id":69,"slug":16,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":16,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":16,"overallStatus":47,"whyStopped":16,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":16},[9],{"measure":10,"description":11,"timeFrame":12},"Composite events of mitral valve repair failure and 1-year reoccurrence of mitral regurgitation","mitral valve repair failure, 1-year reoccurrence of mitral regurgitation","1 year",[14,17,19,21],{"measure":15,"description":16,"timeFrame":12},"Individual occurrence of composite endpoints of mitral valve repair failure and 1-year reoccurrence of mitral regurgitation",null,{"measure":18,"description":16,"timeFrame":12},"The incidence of secondary transfer, perioperative complications",{"measure":20,"description":16,"timeFrame":12},"Intraoperative conditions including extracorporeal circulation time, aortic occlusion time",{"measure":22,"description":16,"timeFrame":12},"The recurrence rate of residual mitral valve regurgitation",{"allocation":24,"interventionModel":25,"interventionModelDescription":16,"primaryPurpose":26,"observationalModel":16,"timePerspective":16,"maskingInfo":27},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":28,"maskingDescription":16,"whoMasked":16},"NONE",[30,36],{"label":31,"type":32,"description":33,"interventionNames":34},"RT3D-TEE-guided mitral valve repair","EXPERIMENTAL","Two experienced surgeons and two experienced echocardiography technicians jointly formulated the plan for the TEE-guided mitral valve repair.",[35],"Procedure: RT3D-TEE-guided mitral valve repair",{"label":37,"type":38,"description":16,"interventionNames":16},"Control","NO_INTERVENTION",[40],{"type":41,"name":31,"description":42,"armGroupLabels":43,"otherNames":16},"PROCEDURE","RT3D-TEE forms a surgical plan before surgery and 3 to 4 senior doctors with more than 50 cases of mitral valve repair perform the procedure.",[31],[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Fuwai Hospital,Chinese Academy of Medical Sciences","RECRUITING","Beijing","Beijing Municipality","100044","China","CN",{"type":54,"coordinates":55},"Point",[56,57],116.39723,39.9075,{"lat":57,"lon":56},[60],{"name":61,"role":62,"phone":63,"phoneExt":16,"email":64},"Sheng Liu, MD","CONTACT","86-13501331366","liusheng@fuwai.com",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":16,"oldOrganization":16},"SPONSOR_INVESTIGATOR","Sheng Liu","Principal Investigator","100484989",false,"NCT05595226","Effect of RT3D-TEE-guided Mitral Valve Repair on Outcomes in Patients With Degenerative Mitral Valve Disease","TEEMR","Inclusion Criteria:\n\n* Diagnosed with chronic primary degenerative mitral regurgitation by the preoperative echocardiogram.\n* Informed consent was obtained\n\nExclusion Criteria:\n\n* Re-operation of mitral regurgitation\n* Concurrent surgical plan for congenital heart disease, coronary artery bypass grafting, aortic valve surgery, radiofrequency ablation of atrial fibrillation and other cardiac surgeries.\n* Mitral valve replacement\n* Unable to undergo TEE","ALL","18 Years","80 Years",{"count":79,"type":80},338,"ESTIMATED","INTERVENTIONAL",[83],"NA","The aim of this randomized controlled trial to investigate the effects of Real-time 3D transesophageal echocardiography (RT3D-TEE)-guided mitral valve repair on surgical failure and 1-year reoccurrence of mitral valve regurgitation in patients with degenerative mitral value disease.",[86],"Degenerative Mitral Valve Disease","2022-10-26",{"date":89,"type":90},"2022-10-28","ACTUAL",{"date":92,"type":90},"2021-12-31",{"date":94,"type":80},"2026-12-31",{"name":67,"class":6},1]