About this trial
Patellofemoral Pain Syndrome (PFPS) is a frequent cause of anterior knee pain in young, physically active individuals, especially females, and is commonly managed with quadriceps and hip-focused exercises. However, the role of neural factors has been largely overlooked. The saphenous nerve, which supplies sensation to the anteromedial knee, may become irritated or entrapped and contribute to pain and neuromuscular dysfunction in PFPS. This study suggests that manual therapy targeting the saphenous nerve could improve pain, function, and balance, providing a more holistic approach to PFPS rehabilitation.
Eligibility criteria
Qualifiers
None
Disqualifiers
Knee replacement
An intraarticular injection within the past 3 months
Previous operative treatment or arthroscopy, other secondary knee-related problems (bursitis, tendinopathy, osteochondritis, neuromas, intraarticular pathology (such as osteoarthritis), tumor, and rheumatologic diseases
Diabetic neuropathic pain or fibromyalgia
Trial design
Treatments tested in this trial
- Saphenous nerve release
Treatment groups
Locations
1Sponsors and collaborators
Cairo University
Lead sponsor