Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-15
SponsorUniversity Hospital, Angers
About this trial
The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment. The aim of the study is to know if an effect is still identifiable after 2 weeks of treatment by performing sleep EEG recordings after 2 and 4 weeks of treatment, respectively.
Eligibility criteria
Qualifiers
Diagnosis of epilepsy syndromes of childhood with sleep activation
Failure of at least two anti-epileptic drugs (AED)
Sleep EEG performed in the last 7 days before inclusion and showing interictal epileptiform discharges (baseline EEG)
Disqualifiers
Previous trial with sulthiame
More than 2 AED at inclusion
Use of corticosteroids at inclusion
Change in the anti-epileptic treatment in the 7 days before baseline EEG
Trial design
Treatments tested in this trial
- Sulthiame
Treatment groups
No treatment groups listed
Locations
3Angers University Hospital, Pediatric department49000, Angers France
Strasbourg University Hospital, Pediatric department67000, Strasbourg France
Toulouse University Hospital, Pediatric Neurology Department31000, Toulouse France
Sponsors and collaborators
University Hospital, Angers
Lead sponsor
Source ClinicalTrials.gov