About this trial

Prospective double blind randomized controlled trial. By randomizing patients undergoing kidney transplantation into a conventional catecholamine drug (dobutamine) blood pressure maintenance group and a terlipressin-complexed dobutamine group, the investigators compared the effect of intraoperative blood pressure maintenance and the dosage of the vasoactive drug, postoperative graft function, delayed graft function, and other related complications between the two groups, in order to demonstrate whether the use of terlipressin for blood pressure regulation during kidney transplantation is superior to the existing treatments.

Eligibility criteria

Qualifiers

Patients with end-stage renal disease aged 18 years or above

Disqualifiers

simultaneous multiple organ transplantation

known allergy to study medication

known pregnancy status

cancellation of surgery due to grafts or personal reasons

Trial design

Treatments tested in this trial

  • terlipressin
  • Placebo (Normal Saline)

Treatment groups

150 Participants
are divided into 2 treatment groups

Locations

1
Beijing Friendship Hospital Beijing China

Sponsors and collaborators

Beijing Friendship Hospital

Lead sponsor