[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598006":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":21,"studyPopulation":13,"armGroups":22,"interventions":35,"overallOfficials":45,"centralContacts":49,"locations":57,"responsibleParty":69,"collaborators":13,"id":72,"slug":13,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":13,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":13,"overallStatus":92,"whyStopped":13,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Suez Canal University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"clinically: A)Loss of crestal bone. B)Stability of implant. Radiographically: crestal bone loss by periapical radiograph in millimeters.","the loss of crestal bone after implant insertion using periodontal probe in millimeters.\n\nimplant stability using OSTELL device. Postoperative follow up using periapical radiographs to evaluate crestal bone loss in millimeters will be after, one ,three months and six months by standardized parallel periapical digital technique radiograph .The radiographs will be done by using: The Kavo Scan eXamTM One and the Rinn extension cone paralleling (XCP)periapical film holder will be used to achieve standardization of digital radiographs.","clinically: Loss of crestal bone by periodontal prop assessed in millimeters in six months Stability of implant by OSTTEL assessed as ISQ values in six months crestal bone loss in millimeters will be one ,three months and six months.",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":18,"observationalModel":13,"timePerspective":13,"maskingInfo":19},"RANDOMIZED","PARALLEL","vitamin D solution mixed with xenograft around immediate implant","TREATMENT",{"masking":20,"maskingDescription":13,"whoMasked":13},"NONE","Effect of Vitamin D on Bone Regeneration .Vitamin D is known for its role in the skeletal system. Vit D deficiency is also widely researched for its effects on the healing of fractures, bone defects and osseointegration of implants. There are studies that investigated the effects of dietary supplementation with vitamin D to reduce vitamin D deficiency but increasing the serum level of this vitamin takes time therefore, an attempt has been made to combat the effect of vitamin D deficiency through topical application. up to the knowledge, upon search of literatures, there is not enough studies that correlate topical application of vitamin D with xenograft mixture as filling space material. this study is to Assess immediate implant with topical vitamin D and xenograft mixture clinically and Radiographically.",[23,29],{"label":24,"type":25,"description":26,"interventionNames":27},"vit D mixed with xenograft","ACTIVE_COMPARATOR","Topical application of vitamin D solution mixed with xenograft in the jumping gap around immediate implant",[28],"Drug: vit D mixed with xenograft",{"label":30,"type":31,"description":32,"interventionNames":33},"only xenograft without vit D","PLACEBO_COMPARATOR","grafting the jumping gap with xenograft only around immediate implant",[34],"Drug: only xenograft without vit D",[36,41],{"type":37,"name":24,"description":26,"armGroupLabels":38,"otherNames":39},"DRUG",[24],[40],"cholecalciferol",{"type":37,"name":30,"description":32,"armGroupLabels":42,"otherNames":43},[30],[44],"xenotransplant",[46],{"name":47,"affiliation":5,"role":48},"mohamed elsaeed ibrahim, master","PRINCIPAL_INVESTIGATOR",[50,54],{"name":47,"role":51,"phone":52,"phoneExt":13,"email":53},"CONTACT","+201150315750","mohamedelsaeed683@gmail.com",{"name":55,"role":51,"phone":56,"phoneExt":13,"email":13},"Mohamed Nageh Gad El-Hak, Lecturer","+201002061808",[58],{"facility":59,"status":13,"city":60,"state":13,"zip":13,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":13},"oral and maxillofacial surgery depertment of oral and dental medicine faculty Suez canal university","Ismailia","Egypt","EG",{"type":64,"coordinates":65},"Point",[66,67],32.27225,30.60427,{"lat":67,"lon":66},{"type":48,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Mohamed elsaeed","master candidate oral and maxillofacial surgery","100598006",false,"NCT07065877","Effect of Vitamin D on Crestal Bone Loss Around Immediate Implant After Mandibular Premolars and Molars Extraction","Clinical and Radiographic Assessment Of Immediate Implant With Topical Vitamin D and Xenograft Mixture: A Randomized Controlled Study","vitD","Inclusion Criteria:\n\n* The American Society of Anesthesiologist (ASA) I , II\n* Both Genders. 3- Patients having unrestorable tooth on the posterior mandibular region\n* Age\\>20\n* The patient who have complete their facial growth and teeth eruption\n* No bone disease or lesion in propose implant site\n\nExclusion Criteria:\n\n* Poor oral hygiene patients and\u002For patients\n* Patients with active acute infection.\n* Patients with bad oral habits.\n* Pregnant or lactating women.\n* Heavy smokers.\n* Alcohol and drug addicts.\n* Diabetes disease",true,"ALL","20 Years","60 Years",{"count":84,"type":85},20,"ESTIMATED","INTERVENTIONAL",[88],"NA","What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant insertion in the posterior region of mandible?",[91],"Crestal Bone Loss","NOT_YET_RECRUITING","2025-07-11",{"date":95,"type":96},"2025-07-15","ACTUAL",{"date":98,"type":85},"2025-07-20",{"date":100,"type":85},"2027-01-01",{"name":5,"class":6},1]