[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100412463":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":29,"responsibleParty":65,"collaborators":67,"id":76,"slug":25,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":25,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":25,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":25,"overallStatus":32,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D","ACTIVE_COMPARATOR","Vitamin D 50,000 IU\u002F week for 4 weeks, followed by 50,000 IU once every 2 weeks for 52 weeks Those who remain anovulatory after 6 months will be treated with a 6-month course of letrozole (2.5mg to 7.5mg for 5 days per cycle titrated according to response) for ovulation induction.",[13],"Dietary Supplement: Vitamin D",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Placebo tablets with same external appearance for 52 weeks Those who remain anovulatory after 6 months will be treated with a 6-month course of letrozole (2.5mg to 7.5mg for 5 days per cycle titrated according to response) for ovulation induction.",[19],"Other: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Vitamin D supplementation",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Placebo tablets with the same external appearance",[15],[30,46,55],{"facility":31,"status":32,"city":33,"state":25,"zip":25,"country":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Kwong Wah Hospital","RECRUITING","Hong Kong",{"type":35,"coordinates":36},"Point",[37,38],114.17469,22.27832,{"lat":38,"lon":37},[41],{"name":42,"role":43,"phone":44,"phoneExt":25,"email":45},"Shui Fan Lai, MBBS, MRCOG","CONTACT","+852 35175183","lsf087@ha.org.hk",{"facility":47,"status":48,"city":33,"state":25,"zip":25,"country":33,"cosmosGeoPoint":49,"geoPoint":51,"contacts":52},"Princess Margaret Hospital","NOT_YET_RECRUITING",{"type":35,"coordinates":50},[37,38],{"lat":38,"lon":37},[53],{"name":54,"role":43,"phone":25,"phoneExt":25,"email":25},"Rebecca S.F. Wan, MBBS, MRCOG",{"facility":56,"status":32,"city":33,"state":25,"zip":25,"country":33,"cosmosGeoPoint":57,"geoPoint":59,"contacts":60},"Queen Mary Hospital, University of Hong Kong",{"type":35,"coordinates":58},[37,38],{"lat":38,"lon":37},[61],{"name":62,"role":43,"phone":63,"phoneExt":25,"email":64},"Jennifer Ka Yee Ko, MBBS","22554647","jenko@hku.hk",{"type":66,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[68,69,72,74],{"name":31,"class":6},{"name":70,"class":71},"Princess Margaret Hospital, Hong Kong","OTHER_GOV",{"name":73,"class":6},"Pamela Youde Nethersole Eastern Hospital",{"name":75,"class":6},"The Queen Elizabeth Hospital","100412463",false,"NCT04650880","Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome","A Randomized Double-blind Controlled Trial on the Effect of Vitamin D on Ovulation Rate of Women With Polycystic Ovary Syndrome","Inclusion Criteria:\n\n* Premenopausal\n* Aged 18-40 years\n* Irregular long menstrual cycles (\\>35 days)\n* PCOS according to the Rotterdam criteria\n* Agree for transvaginal ultrasound\n\nExclusion Criteria:\n\n* Use of hormonal medication (including contraception) within 3 months prior to study inclusion, except the use of a progestogen to induce withdrawal bleeding every 3 months\n* History of any medical condition or medications that may predispose to vitamin D sensitivity, altered vitamin D metabolism and\u002F or hypercalcemia, including active tuberculosis or current therapy for tuberculosis, sarcoidosis, history of renal\u002F ureteral stones, parathyroid disease, renal or liver failure or current use of anti-convulsants\n* Use of insulin-sensitizing drugs, lipid lowering drugs or anti-hypertensive\n* Anticipated to use the above medications in the coming one year\n* Known type 2 diabetes mellitus\n* Refusal to join the study\n* Abnormal blood calcium level\n\nFor those on supplements, we asked them to stop their own supplements.","FEMALE","18 Years","40 Years",{"count":86,"type":87},220,"ESTIMATED","INTERVENTIONAL",[90],"NA","This is a randomized double-blind controlled trial on the effect of vitamin D supplementation to assess the ovulation rate of women with polycystic ovary syndrome (PCOS) and other reproductive, endocrine and metabolic outcomes after one year of treatment.",[93,94],"Polycystic Ovary Syndrome","Anovulation","2024-05-13",{"date":97,"type":98},"2024-05-14","ACTUAL",{"date":100,"type":98},"2021-01-26",{"date":102,"type":87},"2026-12-31",{"name":5,"class":6},3]