[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499913":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":57,"collaborators":60,"id":64,"slug":25,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":25,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"AdventHealth Translational Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Attention control","SHAM_COMPARATOR","Static stretching",[13],"Behavioral: Progressive stretching",{"label":15,"type":16,"description":17,"interventionNames":18},"Aerobic exercise","EXPERIMENTAL","Aerobic exercise at a dose of 225 minutes per week",[19],"Behavioral: Aerobic exercise",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Moderate- to vigorous-intensity aerobic exercise",[15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Progressive stretching","Statistic stretching of eight major muscle groups",[9],[31],{"name":32,"affiliation":33,"role":34},"Justin C. Brown, Ph.D.","AdventHealth","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","407-303-5600","Justin.Brown4@AdventHealth.com",[41],{"facility":33,"status":42,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Orlando","Florida","32804","United States",{"type":48,"coordinates":49},"Point",[50,51],-81.37924,28.53834,{"lat":51,"lon":50},[54],{"name":55,"role":37,"phone":56,"phoneExt":25,"email":39},"Justin C Brown, Ph.D.","4073035600",{"type":34,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Justin Brown","Director, Exercise & Cancer Biology Research Program",[61],{"name":62,"class":63},"National Cancer Institute (NCI)","NIH","100499913",false,"NCT05789433","Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer","RESTORE","Inclusion Criteria:\n\n* Age ≥18 years\n* Histologically confirmed stage I, II, or III colon or rectal cancer\n* Completed surgical resection with curative intent\n* Completed other cancer-directed treatments\n* Engage in \\\u003C150 minutes per week of moderate- to vigorous-intensity structured endurance exercise\n* No planned major surgery during the study period\n* Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire\n* Ability to provide written informed consent\n* Provide written approval by a qualified healthcare professional\n* Willing to be randomized\n\nExclusion Criteria:\n\n* Evidence of metastatic or recurrent colorectal cancer\n* Concurrently actively treated other (non-colorectal) cancer\n* Scheduled to receive other postoperative cancer-directed treatment(s)\n* Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks\n* Currently participating in another study with competing outcomes\n* Contraindications to magnetic resonance imaging\n* Any dietary condition or restriction that would limit tolerance of a mixed meal challenge\n* Any other cardiovascular, pulmonary, orthopedic, neurologic, psychiatric, or other condition that, in the investigator's opinion, would preclude participation or successful compliance with the protocol\n* Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol","ALL","18 Years",{"count":73,"type":74},70,"ESTIMATED","INTERVENTIONAL",[77],"NA","The goal of this clinical trial is to quantify the effects of aerobic exercise training compared to attention control on intermuscular adipose tissue in colorectal cancer survivors.",[80,81],"Colonic Neoplasms","Rectal Neoplasms","2025-07-01",{"date":84,"type":85},"2025-07-03","ACTUAL",{"date":87,"type":85},"2023-05-01",{"date":89,"type":74},"2027-03-01",{"name":5,"class":6},1]