Population aging has become a significant global concern, and Taiwan is set to officially enter the "super-aged society" in 2025. As individuals age, various physiological functions gradually decline, including a reduction in muscle mass, which is a key aspect of the aging process.
This interventional study aims to investigate the effects of leucine-rich protein combined with polyunsaturated fatty acid supplementation on middle-aged and elderly individuals (aged 50 and above) who are at high risk for sarcopenia.
Age ≥ 50 years
ASMI < 7 kg/m2 in men
ASMI < 5.7 kg/m2 in women
Grip strength < 28 kg in men
People who are allergic to supplements
cancer
heart failure
kidney disease
Parallel
Animal-Based Oil Group
Dietary supplementParticipants in animal-based oil group will follow a diet in which the primary fat source is animal-based oil. The diet will supplement for 12 weeks.
Plant-Based Oil Group
Dietary supplementParticipants in plant-based oil group will follow a diet in which the primary fat source is plant-based oil. The diet will supplement for 12 weeks.
muscle mass
Utilize Bioelectrical Impedance Analysis (BIA) to measure the Appendicular Skeletal Muscle Mass Index Level (ASMI) (kg/m\^2)
muscle function
utilize handgrip dynamometer to measure the hand grip strength (kg).
physical function
To assess the participant's walking speed over a 4-meter distance.
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Chang Gung Memorial Hospital
Lead sponsor
Chang Gung University
Collaborator
