Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-70
SponsorIntegrative Skin Science and Research

About this trial

The purpose of this study is to evaluate how supplementation will alter the skin and the gut barrier and inflammation in those with rosacea.

Eligibility criteria

Qualifiers

Males and females 30 to 70 years of age

The presence of mild to moderate rosacea (erythematotelangiectatic or papulopustular)

High sensitivity C-reactive protein (hs-CRP) that is greater than or equal to 1.0 mg/L

Disqualifiers

The presence of severe rosacea as noted by the investigator global assessment.

Those who are unwilling to discontinue oral supplementation, or supplement ingredients found in the study's oral product 1 month prior to enrollment.

Discontinuation of oral L-glutamine or L-glutamine containing supplement 1 month prior to enrollment

Those who are unwilling to discontinue topical benzoyl peroxide or retinoids for 2 weeks prior to enrollment.

Trial design

Treatments tested in this trial

  • Skin Barrier Oral Supplement

Treatment groups

24 Participants
are divided into 1 treatment group

Locations

1
Integrative Skin and Research95815, SacramentoCalifornia, United States

Sponsors and collaborators

Integrative Skin Science and Research

Lead sponsor