[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568309":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":30,"locations":35,"responsibleParty":52,"collaborators":12,"id":55,"slug":12,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":12,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":12,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":37,"whyStopped":12,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Guelph","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal sleep","NO_INTERVENTION","During this arm, participants will be asked to come to the lab for testing after a night of normal sleep. Normal sleep will be defined as participants habitual sleep-wake timing.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Partial sleep deprivation","EXPERIMENTAL","During this arm, participants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\\~40% of normal sleep duration).",[18],"Other: Partial sleep deprivation",[20],{"type":6,"name":14,"description":21,"armGroupLabels":22,"otherNames":12},"Participants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\\~40% of normal sleep duration).",[14],[24,27],{"name":25,"affiliation":5,"role":26},"Julian Bommarito, MSc","STUDY_DIRECTOR",{"name":28,"affiliation":5,"role":29},"Philip Millar, PhD","PRINCIPAL_INVESTIGATOR",[31],{"name":25,"role":32,"phone":33,"phoneExt":12,"email":34},"CONTACT","9052209829","jbomma01@uoguelph.ca",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Guelph","Ontario","N1G 2W1","Canada",{"type":43,"coordinates":44},"Point",[45,46],-80.25599,43.54594,{"lat":46,"lon":45},[49,50],{"name":25,"role":32,"phone":33,"phoneExt":12,"email":34},{"name":25,"role":51,"phone":12,"phoneExt":12,"email":12},"SUB_INVESTIGATOR",{"type":29,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Philip Millar","Associate Professor","100568309",false,"NCT06679543","Effects of Partial Sleep Deprivation on Cardiac Output During Cycling","Inclusion Criteria:\n\n* Free of known cardiovascular or metabolic diseases or sleep disorders\n* No history of smoking (within the past 3 months)\n* Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+)\n* No prescription of chronic medications other than oral contraceptives\n* Able to abide by sleep protocols for all visits\n* Individuals who are not allergic to ultrasound gel\n* Individuals who are not pregnant\n\nExclusion Criteria:\n\n* Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders\n* Has a history of smoking (within the past 3 months)\n* Not ready to engage in physical activity as assessed by the PAR-Q+\n* Individuals prescribed chronic medications other than oral contraceptives\n* Unable to abide by sleep protocols for any testing visit\n* Allergic to ultrasound gel\n* Pregnancy",true,"ALL","18 Years","50 Years",{"count":65,"type":66},30,"ESTIMATED","INTERVENTIONAL",[69],"NA","The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are:\n\n* Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation?\n* Do sex differences exist?\n\nParticipants will:\n\n* Visit the lab after a night of normal sleep and a night of partial sleep deprivation.\n* Keep a daily diary of their sleep and food\u002Fbeverage intake.\n* Perform maximal and submaximal exercise on a cycle ergometer.",[72],"Sleep Deprivation",[74,75,76,77],"exercise blood pressure","cardiac output","plasma volume","sleep deprivation","2026-04-27",{"date":80,"type":81},"2026-04-28","ACTUAL",{"date":83,"type":81},"2025-01-02",{"date":85,"type":66},"2026-12",{"name":5,"class":6},1]