[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562710":3},{"organization":4,"outcomesModule":7,"designInfo":32,"detailedDescription":42,"studyPopulation":31,"armGroups":43,"interventions":62,"overallOfficials":76,"centralContacts":80,"locations":85,"responsibleParty":104,"collaborators":106,"id":110,"slug":31,"hasResults":111,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":31,"eligibilityCriteria":115,"healthyVolunteers":116,"sex":117,"minAge":118,"maxAge":31,"enrollmentInfo":119,"targetDuration":31,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":128,"overallStatus":87,"whyStopped":31,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":142},{"fullName":5,"class":6},"University of Regina","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":31,"otherOutcomes":31},[9,13,16,19,22,25,28],{"measure":10,"description":11,"timeFrame":12},"Whole-body lean mass (kg)","Bioelectrical impedance analysis","baseline, week 16",{"measure":14,"description":15,"timeFrame":12},"Muscle Hypertrophy (cm)","B-mode ultrasound",{"measure":17,"description":18,"timeFrame":12},"Strength (kg)","1-repetition maximum leg press and chest press",{"measure":20,"description":21,"timeFrame":12},"Endurance (number of repetitions to fatigue)","Leg press and chest press",{"measure":23,"description":24,"timeFrame":12},"Power (feet)","medicine ball throw",{"measure":26,"description":27,"timeFrame":12},"Balance (Centre of Pressure)","Force Plate",{"measure":29,"description":30,"timeFrame":12},"Gait Speed (meters)","Walking distance",null,{"allocation":33,"interventionModel":34,"interventionModelDescription":31,"primaryPurpose":35,"observationalModel":31,"timePerspective":31,"maskingInfo":36},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":37,"maskingDescription":31,"whoMasked":38},"TRIPLE",[39,40,41],"PARTICIPANT","INVESTIGATOR","OUTCOMES_ASSESSOR","Resistance-band training is safe, conveient, easy-to-use, eliminates potential barriers to exercise participation (i.e., lack of transportation to and from commercial training facilities) and results in high exercise compliance and adherence. Further, resistance-band training results in similar improvements in muscle performance and functional ability compared to traditional resistance-type training using free-weights and machines.\n\nCreatine is a naturally occurring nitrogen-containing compound produced in the body in the liver and brain and can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products.\n\nEvidence-based research shows that creatine supplementation, when ingested during a resistance exercise training program, improves measures of lean mass and muscle growth, muscle performance and functional ability. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.",[44,49,53,57],{"label":45,"type":46,"description":31,"interventionNames":47},"Creatine Bolus 5","EXPERIMENTAL",[48],"Dietary Supplement: Creatine Bolus 5",{"label":50,"type":46,"description":31,"interventionNames":51},"Creatine Bolus 3",[52],"Dietary Supplement: Creatine Bolus 3",{"label":54,"type":46,"description":31,"interventionNames":55},"Creatine Intermittent 5",[56],"Dietary Supplement: Creatine Intermittent 5",{"label":58,"type":59,"description":31,"interventionNames":60},"Placebo","PLACEBO_COMPARATOR",[61],"Dietary Supplement: Placebo",[63,67,70,73],{"type":64,"name":45,"description":65,"armGroupLabels":66,"otherNames":31},"DIETARY_SUPPLEMENT","(Serving 1: 5 grams of creatine + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).",[45],{"type":64,"name":50,"description":68,"armGroupLabels":69,"otherNames":31},"(Serving 1: 3 grams of creatine + 5 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).",[50],{"type":64,"name":54,"description":71,"armGroupLabels":72,"otherNames":31},"(Serving 1: 2.5 grams of creatine + 5.5 grams of placebo in the morning, Serving 2: 2.5 grams of creatine + 5.5 grams of placebo at least 6 hours after Serving 1).",[54],{"type":64,"name":58,"description":74,"armGroupLabels":75,"otherNames":31},"(Serving: 8 grams of placebo in the morning; Servings 2: 8 grams of placebo at least 6 hours after Serving 1).",[58],[77],{"name":78,"affiliation":5,"role":79},"Darren Candow","PRINCIPAL_INVESTIGATOR",[81],{"name":78,"role":82,"phone":83,"phoneExt":31,"email":84},"CONTACT","306-585-4906","Darren.Candow@uregina.ca",[86],{"facility":5,"status":87,"city":88,"state":89,"zip":90,"country":91,"countryCode":92,"cosmosGeoPoint":93,"geoPoint":98,"contacts":99},"RECRUITING","Regina","Saskatchewan","S4S4H4","Canada","CA",{"type":94,"coordinates":95},"Point",[96,97],-104.6178,50.45008,{"lat":97,"lon":96},[100,103],{"name":101,"role":82,"phone":102,"phoneExt":31,"email":84},"Darren G Candow, PhD","3062090280",{"name":101,"role":82,"phone":31,"phoneExt":31,"email":31},{"type":79,"investigatorFullName":78,"investigatorTitle":105,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Professor",[107],{"name":108,"class":109},"Iovate Health Sciences International Inc","INDUSTRY","100562710",false,"NCT06606704","Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults","Effects of Resistance-band Training and Creatine Supplementation in Healthy Older Adults","Inclusion Criteria:\n\n* if you are 50 years of age and older\n* if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.\n\nExclusion Criteria:\n\n* if you have taken creatine supplements within 30 days prior to the start of the study\n* if you have pre-existing allergies to the placebo (corn-starch maltodextrin).",true,"ALL","50 Years",{"count":120,"type":121},52,"ESTIMATED","INTERVENTIONAL",[124],"NA","The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).\n\nA secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).",[127],"Aging",[127,129,130,131,132],"Creatine","Resistance-Bands","Muscle","Strength","2024-09-18",{"date":135,"type":136},"2024-09-23","ACTUAL",{"date":138,"type":136},"2024-08-20",{"date":140,"type":121},"2025-07-30",{"name":5,"class":6},1]